DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7509 and AgaP_AGAP007060

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_565144.3	Gene:	AgaP_AGAP007060 / 3290298	VectorBaseID:	AGAP007060	Length:	1185	Species:	Anopheles gambiae

Alignment Length:	482	Identity:	124/482 - (25%)
Similarity:	208/482 - (43%)	Gaps:	97/482 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 ISSDTRNCSLNACESLGIVSQLLMLINSMPNGTQSAANDKKPPKSKANGHNDGDVNGGEINAMSH 111
            :|..|..|.|   |:|.:|..|::|                          .|||...:.|..:.
Mosquito     1 MSEGTGFCVL---EALPLVLLLILL--------------------------GGDVQAYKFNLSAE 36

  Fly   112 LANFDLVKRVRQIESRLRSVEQPVWHLATGSQIEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVT 176
            ....::     |.|..|.|:..|......|.::              ||
Mosquito    37 YGTVEV-----QFEKSLVSIVPPSLFEDNGQKV--------------DT---------------- 66

  Fly   177 QVIPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQL 241
                :.|..:|:.|     :..|||.....||.|.:..|.:..|...:|::..:|..:....|::
Mosquito    67 ----LVMREVDVQR-----VDADTFTKAVALKSLQMHRNRIPKLFNRMFRNATNLRRINFGGNRI 122

  Fly   242 EDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEEL 306
            :.::..||..|.||:::.||:|:|.:||..:|.....||.:.:..|:|...|..:..|..:|:||
Mosquito   123 DAVEEYTFEGLENLSVIRLSRNKIPVLPRKLFAGLSSLTSLLLDHNRILELPEGIFEDLTILDEL 187

  Fly   307 DMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNN 371
            .:|.|.:..|:..|.:.|.:|..|....|:|:.|:.|.||.|.:|:.|:|.:||::||:...|..
Mosquito   188 YLSFNFLERLTRNSFKGLVELDNLALHNNRISTIEPDTFASLATLQYLTLGSNRLTSLAPETFIA 252

  Fly   372 LANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTL 436
            ...|..|||:.|:::.:..:.|.....|.||.:..||:..:.:|||.|.:.|..|.:..|.:.:|
Mosquito   253 QTKLAKLDLSVNQLAELPKDLFRYTTALKELKISNNSLKELHSDLFANTAKLEDLVISHNEVESL 317

  Fly   437 EADDFQGLNNLKILLLNNNILKN-----FDA----RA---------------FEPLSQLEKLRID 477
            :|..|:.|..|::|||.||.:.:     |||    ||               |..|..|:||.:.
Mosquito   318 DAALFRNLRKLEMLLLENNNIGHIFPGTFDALQSLRALDLNQNGIMTIEGGLFRALRVLDKLYLQ 382

  Fly   478 SNKLMFLPHGALHGLKNLVAVKLDKNP 504
            :|.:..:...:|.|...|..:.|:|||
Mosquito   383 NNLISMVSGYSLEGAVQLTELYLNKNP 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	14/58 (24%)
		leucine-rich repeat	187..206	CDD:275380	5/18 (28%)
		LRR_RI	<201..386	CDD:238064	57/184 (31%)
		leucine-rich repeat	207..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..254	CDD:275380	5/22 (23%)
		LRR_8	253..313	CDD:290566	20/59 (34%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		LRR_8	303..361	CDD:290566	21/57 (37%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	9/22 (41%)
		LRR_8	349..407	CDD:290566	17/57 (30%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..398	CDD:275380	6/22 (27%)
		LRR_8	398..>443	CDD:290566	15/44 (34%)
		leucine-rich repeat	399..422	CDD:275380	9/22 (41%)
		leucine-rich repeat	423..443	CDD:275380	6/19 (32%)
		leucine-rich repeat	471..494	CDD:275380	6/22 (27%)
		LRRCT	503..554	CDD:214507	2/2 (100%)
AgaP_AGAP007060	XP_565144.3	leucine-rich repeat	88..111	CDD:275380	6/22 (27%)
		LRR_8	110..170	CDD:290566	17/59 (29%)
		leucine-rich repeat	112..135	CDD:275380	5/22 (23%)
		leucine-rich repeat	136..159	CDD:275380	8/22 (36%)
		leucine-rich repeat	160..183	CDD:275380	6/22 (27%)
		LRR_8	166..218	CDD:290566	15/51 (29%)
		leucine-rich repeat	186..207	CDD:275380	7/20 (35%)
		LRR_8	207..266	CDD:290566	22/58 (38%)
		leucine-rich repeat	208..231	CDD:275380	9/22 (41%)
		leucine-rich repeat	232..255	CDD:275380	8/22 (36%)
		LRR_RI	236..481	CDD:238064	52/174 (30%)
		LRR_8	254..312	CDD:290566	17/57 (30%)
		leucine-rich repeat	256..279	CDD:275380	6/22 (27%)
		leucine-rich repeat	280..303	CDD:275380	9/22 (41%)
		LRR_8	303..362	CDD:290566	18/58 (31%)
		leucine-rich repeat	304..327	CDD:275380	7/22 (32%)
		leucine-rich repeat	328..351	CDD:275380	9/22 (41%)
		LRR_8	351..410	CDD:290566	15/59 (25%)
		leucine-rich repeat	352..375	CDD:275380	4/22 (18%)
		leucine-rich repeat	376..399	CDD:275380	6/22 (27%)
		LRR_8	421..481	CDD:290566
		leucine-rich repeat	423..446	CDD:275380
		leucine-rich repeat	447..468	CDD:275380
		LRR_RI	448..690	CDD:238064
		leucine-rich repeat	471..493	CDD:275380
		LRR_8	492..551	CDD:290566
		leucine-rich repeat	494..517	CDD:275380
		leucine-rich repeat	518..540	CDD:275380
		leucine-rich repeat	541..562	CDD:275380
		leucine-rich repeat	563..583	CDD:275380
		LRR_8	582..642	CDD:290566
		leucine-rich repeat	584..604	CDD:275380
		leucine-rich repeat	608..631	CDD:275380
		LRR_8	630..690	CDD:290566
		leucine-rich repeat	632..655	CDD:275380
		leucine-rich repeat	656..679	CDD:275380
		leucine-rich repeat	680..703	CDD:275380
		leucine-rich repeat	704..750	CDD:275380
		LRR_RI	<764..978	CDD:238064
		LRR_8	775..834	CDD:290566
		leucine-rich repeat	775..799	CDD:275380
		leucine-rich repeat	800..823	CDD:275380
		leucine-rich repeat	824..847	CDD:275380
		LRR_8	848..906	CDD:290566
		leucine-rich repeat	848..871	CDD:275380
		leucine-rich repeat	872..895	CDD:275380
		LRR_RI	875..1133	CDD:238064
		LRR_8	895..953	CDD:290566
		leucine-rich repeat	896..919	CDD:275380
		leucine-rich repeat	920..941	CDD:275380
		leucine-rich repeat	943..966	CDD:275380
		leucine-rich repeat	1032..1080	CDD:275380
		leucine-rich repeat	1057..1078	CDD:275378
		leucine-rich repeat	1081..1104	CDD:275380
		leucine-rich repeat	1105..1123	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BET7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770