DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Lingo4

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_796224.1 Gene:Lingo4 / 320747 MGIID:2444651 Length:618 Species:Mus musculus


Alignment Length:444 Identity:123/444 - (27%)
Similarity:180/444 - (40%) Gaps:92/444 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 LATGSQIEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPMNMVNIDLSRNILSTLHKDTFR 202
            |..|..|  :.|.: ||.|...|::..|.:..|.::|  ..:|::...:|||.|.|..|.:....
Mouse    47 LLPGGSI--SSCPT-VCDCTSQTRAVFCAHRRLDTIP--GGLPLDTELLDLSGNRLWGLQRGMLS 106

  Fly   203 GLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGM 267
            .|..|:|||:|:|.|..|....|..|.|||.||:|.|:|..:....|..|..|.:|||..|:|.:
Mouse   107 RLGQLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIVGPGIFSGLTALTLLDLRLNQIVL 171

  Fly   268 LPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDF 332
            ..:..|                                        |||.|        |:.|:.
Mouse   172 FLDGAF----------------------------------------SELGS--------LQQLEV 188

  Fly   333 GWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELN 397
            |.|.:..:....||||..|.|::|....:|::.|.....|..||.|.|....|..:...|...|.
Mouse   189 GDNHLVFVAPGAFAGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIERLPAGALRGLG 253

  Fly   398 NLNELFLGQ-NSMSSI-PADLF-LNVS--ALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNIL 457
            .|.||.:.. .|:.:: |..|. ||:|  |:||.     ||:::.......|:.|:||.|:.|.:
Mouse   254 QLKELEIHHWPSLEALDPGSLVGLNLSSLAITRC-----NLSSVPFQALHHLSFLRILDLSQNPI 313

  Fly   458 KNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGL------------------------KNLVAV 498
            ....||...||.:|::||:....|..:...|.|||                        ..||.:
Mouse   314 SAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTL 378

  Fly   499 KLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDL 552
            :|..||..||||.|:|.|..|...   :....|.|.||..:.|.  .|..:.|:
Mouse   379 RLSGNPLTCDCRLLWLLRLRRRLD---FGTSPPACAGPQHVQGK--SLREFSDI 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566 24/58 (41%)
leucine-rich repeat 187..206 CDD:275380 7/18 (39%)
LRR_RI <201..386 CDD:238064 50/184 (27%)
leucine-rich repeat 207..230 CDD:275380 10/22 (45%)
leucine-rich repeat 231..254 CDD:275380 9/22 (41%)
LRR_8 253..313 CDD:290566 7/59 (12%)
leucine-rich repeat 255..278 CDD:275380 7/22 (32%)
leucine-rich repeat 279..302 CDD:275380 0/22 (0%)
LRR_8 303..361 CDD:290566 15/57 (26%)
leucine-rich repeat 303..326 CDD:275380 4/22 (18%)
leucine-rich repeat 327..350 CDD:275380 8/22 (36%)
LRR_8 349..407 CDD:290566 16/58 (28%)
LRR_4 350..390 CDD:289563 11/39 (28%)
leucine-rich repeat 351..374 CDD:275380 6/22 (27%)
leucine-rich repeat 375..398 CDD:275380 7/22 (32%)
LRR_8 398..>443 CDD:290566 14/49 (29%)
leucine-rich repeat 399..422 CDD:275380 9/27 (33%)
leucine-rich repeat 423..443 CDD:275380 4/19 (21%)
leucine-rich repeat 471..494 CDD:275380 8/46 (17%)
LRRCT 503..554 CDD:214507 17/50 (34%)
Lingo4NP_796224.1 LRRNT 56..89 CDD:214470 9/35 (26%)
leucine-rich repeat 69..86 CDD:275380 4/18 (22%)
leucine-rich repeat 87..110 CDD:275380 7/22 (32%)
LRR_8 90..145 CDD:290566 24/54 (44%)
leucine-rich repeat 111..134 CDD:275380 10/22 (45%)
LRR_RI 112..345 CDD:238064 79/285 (28%)
LRR_8 134..193 CDD:290566 25/106 (24%)
leucine-rich repeat 135..158 CDD:275380 9/22 (41%)
leucine-rich repeat 159..182 CDD:275380 10/62 (16%)
LRR_8 182..237 CDD:290566 18/62 (29%)
leucine-rich repeat 183..206 CDD:275380 8/22 (36%)
leucine-rich repeat 207..230 CDD:275380 6/22 (27%)
leucine-rich repeat 231..254 CDD:275380 7/22 (32%)
leucine-rich repeat 255..302 CDD:275380 15/51 (29%)
LRR_8 278..334 CDD:290566 20/60 (33%)
leucine-rich repeat 303..326 CDD:275380 9/22 (41%)
LRR_8 326..385 CDD:290566 12/58 (21%)
leucine-rich repeat 327..350 CDD:275380 8/22 (36%)
leucine-rich repeat 351..369 CDD:275380 0/17 (0%)
leucine-rich repeat 375..387 CDD:275378 5/11 (45%)
IG_like 445..526 CDD:214653
Ig 456..526 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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