DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Rtn4rl1

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_852042.1 Gene:Rtn4rl1 / 303311 RGDID:727812 Length:445 Species:Rattus norvegicus


Alignment Length:323 Identity:90/323 - (27%)
Similarity:123/323 - (38%) Gaps:69/323 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   260 LSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYL 324
            |..|.|..|.:..|..|  :..:.:..|.|....||.....:.|||||:..|:            
  Rat    61 LQNNHITFLQQGHFSPA--MVTLWIYSNNITFIAPNTFEGFVHLEELDLGDNR------------ 111

  Fly   325 TKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHID 389
                       |:..:..:.|.||..|..|.|:...:|||...||..|.:|..|.|..|.|.::.
  Rat   112 -----------QLRTLAPETFQGLVKLHALYLYKCGLSSLPAGIFGGLHSLQYLYLQDNHIEYLQ 165

  Fly   390 GNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNN 454
            .:.||:|.||:.|||..|.:.|:...:|..:..|.||.|..|.|..:....|..|:.|..|.|.|
  Rat   166 DDIFVDLVNLSHLFLHGNKLWSLGQGIFRGLVNLDRLLLHENQLQWVHHKAFHDLHRLTTLFLFN 230

  Fly   455 NILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIR 519
            |.|.........||..||.||                        |:.|.|.|.|||..|..|:|
  Rat   231 NSLTELQGDCLAPLVALEFLR------------------------LNGNAWDCGCRARSLWEWLR 271

  Fly   520 EFVLKLWDGQQPM--CRGPGDLGGHEVGLLRYDDL--CDGQWASMLSLSPRLP--VRKHQIST 576
            .|     .|...:  |..|....|.::..||.:|.  |.|         |..|  ::.|.:||
  Rat   272 RF-----RGSSSVVPCATPELRQGQDLKSLRVEDFRNCTG---------PASPHQIKSHTLST 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566
leucine-rich repeat 187..206 CDD:275380
LRR_RI <201..386 CDD:238064 33/125 (26%)
leucine-rich repeat 207..230 CDD:275380
leucine-rich repeat 231..254 CDD:275380
LRR_8 253..313 CDD:290566 16/52 (31%)
leucine-rich repeat 255..278 CDD:275380 6/17 (35%)
leucine-rich repeat 279..302 CDD:275380 4/22 (18%)
LRR_8 303..361 CDD:290566 13/57 (23%)
leucine-rich repeat 303..326 CDD:275380 6/22 (27%)
leucine-rich repeat 327..350 CDD:275380 4/22 (18%)
LRR_8 349..407 CDD:290566 22/57 (39%)
LRR_4 350..390 CDD:289563 14/39 (36%)
leucine-rich repeat 351..374 CDD:275380 9/22 (41%)
leucine-rich repeat 375..398 CDD:275380 8/22 (36%)
LRR_8 398..>443 CDD:290566 15/44 (34%)
leucine-rich repeat 399..422 CDD:275380 7/22 (32%)
leucine-rich repeat 423..443 CDD:275380 7/19 (37%)
leucine-rich repeat 471..494 CDD:275380 4/22 (18%)
LRRCT 503..554 CDD:214507 17/54 (31%)
Rtn4rl1NP_852042.1 leucine-rich repeat 37..58 CDD:275380
LRR 1 55..76 5/14 (36%)
LRR 2 77..98 5/22 (23%)
leucine-rich repeat 78..101 CDD:275380 4/22 (18%)
LRR_8 85..132 CDD:404697 16/69 (23%)
LRR 3 101..123 8/44 (18%)
leucine-rich repeat 102..126 CDD:275380 10/46 (22%)
PPP1R42 126..>255 CDD:411060 46/152 (30%)
LRR 4 126..147 8/20 (40%)
leucine-rich repeat 127..150 CDD:275380 9/22 (41%)
LRR 5 150..171 6/20 (30%)
leucine-rich repeat 151..174 CDD:275380 8/22 (36%)
LRR_8 174..233 CDD:404697 21/58 (36%)
LRR 6 174..195 8/20 (40%)
leucine-rich repeat 175..198 CDD:275380 7/22 (32%)
LRR 7 198..219 7/20 (35%)
leucine-rich repeat 199..222 CDD:275380 8/22 (36%)
LRR 8 222..243 6/20 (30%)
leucine-rich repeat 223..246 CDD:275380 8/22 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 304..380 7/26 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 401..421
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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