DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Lrrc4b

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_937893.1 Gene:Lrrc4b / 272381 MGIID:3027390 Length:709 Species:Mus musculus


Alignment Length:298 Identity:97/298 - (32%)
Similarity:142/298 - (47%) Gaps:27/298 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 SKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLT 325
            ::.|:..:|.||..:.:.|   |:.:|.||....:..:....||.|.:|:|.:.::..|:...|.
Mouse    75 TRRELAEVPASIPVNTRYL---NLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLP 136

  Fly   326 KLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDL-TTNRISHID 389
            .|.||:...|::..:....|..|..||.|.|.||.|.|:....||.:.:|..||| ...|:.:|.
Mouse   137 SLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYIS 201

  Fly   390 GNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTR---LTLFSNNLTTLEADDFQGLNNLKILL 451
            ..||..|.||..|.||..::..||     |::||.|   |.|..|.|..:....||||.:|:.|.
Mouse   202 EAAFEGLVNLRYLNLGMCNLKDIP-----NLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLW 261

  Fly   452 LNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLAR 516
            |.:..:...:..||:.|..||:|.:..|.||.|||.....|..|..|.|:.|||||:|..|:|:.
Mouse   262 LMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSW 326

  Fly   517 WIREFVLKLWDGQQP-------MCRGPGDLGGHEVGLL 547
            |::|.|        |       .|..|..|.|..:|.|
Mouse   327 WLKETV--------PSNTTCCARCHAPAGLKGRYIGEL 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566
leucine-rich repeat 187..206 CDD:275380
LRR_RI <201..386 CDD:238064 37/125 (30%)
leucine-rich repeat 207..230 CDD:275380
leucine-rich repeat 231..254 CDD:275380
LRR_8 253..313 CDD:290566 14/51 (27%)
leucine-rich repeat 255..278 CDD:275380 4/16 (25%)
leucine-rich repeat 279..302 CDD:275380 5/22 (23%)
LRR_8 303..361 CDD:290566 19/57 (33%)
leucine-rich repeat 303..326 CDD:275380 7/22 (32%)
leucine-rich repeat 327..350 CDD:275380 6/22 (27%)
LRR_8 349..407 CDD:290566 24/58 (41%)
LRR_4 350..390 CDD:289563 16/40 (40%)
leucine-rich repeat 351..374 CDD:275380 10/22 (45%)
leucine-rich repeat 375..398 CDD:275380 9/23 (39%)
LRR_8 398..>443 CDD:290566 16/47 (34%)
leucine-rich repeat 399..422 CDD:275380 7/22 (32%)
leucine-rich repeat 423..443 CDD:275380 7/22 (32%)
leucine-rich repeat 471..494 CDD:275380 10/22 (45%)
LRRCT 503..554 CDD:214507 18/52 (35%)
Lrrc4bNP_937893.1 LRRNT 59..92 CDD:214470 4/16 (25%)
LRR <89..299 CDD:227223 71/217 (33%)
LRR 1 89..110 5/23 (22%)
leucine-rich repeat 90..113 CDD:275380 5/25 (20%)
LRR 2 113..134 6/20 (30%)
leucine-rich repeat 114..137 CDD:275380 7/22 (32%)
LRR 3 137..158 5/20 (25%)
leucine-rich repeat 138..161 CDD:275380 6/22 (27%)
LRR 4 161..182 9/20 (45%)
leucine-rich repeat 162..185 CDD:275380 10/22 (45%)
LRR 5 185..207 8/21 (38%)
leucine-rich repeat 186..210 CDD:275380 9/23 (39%)
LRR 6 210..231 9/25 (36%)
leucine-rich repeat 211..232 CDD:275380 9/25 (36%)
LRR 7 232..253 6/20 (30%)
leucine-rich repeat 233..256 CDD:275380 8/22 (36%)
LRR 8 256..277 5/20 (25%)
leucine-rich repeat 257..280 CDD:275380 6/22 (27%)
LRR 9 280..301 9/20 (45%)
leucine-rich repeat 281..302 CDD:275380 9/20 (45%)
LRRCT 313..363 CDD:214507 18/52 (35%)
I-set 366..455 CDD:400151
Ig strand A 366..369 CDD:409353
Ig strand A' 373..376 CDD:409353
Ig strand B 382..389 CDD:409353
Ig strand C 395..400 CDD:409353
Ig strand C' 403..405 CDD:409353
Ig strand D 414..418 CDD:409353
Ig strand E 421..425 CDD:409353
Ig strand F 435..442 CDD:409353
Ig strand G 445..455 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 496..552
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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