DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and Gp5

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_036927.2	Gene:	Gp5 / 25259	RGDID:	2724	Length:	567	Species:	Rattus norvegicus

Alignment Length:	449	Identity:	124/449 - (27%)
Similarity:	194/449 - (43%)	Gaps:	55/449 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 IPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLR-------- 235
            :|.|:.:|.|.|.....|...:|.|:|||:.|.:|.:.:..:....|.||..|..||
  Rat    48 LPTNLTHILLFRMDRGVLQSHSFSGMTVLQRLMLSDSHISAIDPGTFNDLVKLKTLRLTRNKISH 112

  Fly   236 ----------------IQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINM 284
                            :.:|.|.|:|...|.||.||..|.|::|::..||.::|....:|.|:::
  Rat   113 LPRAILDKMVLLEQLFLDHNALRDLDQNLFQKLLNLRDLCLNQNQLSFLPANLFSSLGKLKVLDL 177

  Fly   285 CDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLR 349
            ..|.:.:.|..||..|:.||:|.:..|::..|.||.:..|..|..|....|.:..|....|..|.
  Rat   178 SRNNLTHLPQGLLGAQIKLEKLLLYSNRLMSLDSGLLANLGALTELRLERNHLRSIAPGAFDSLG 242

  Fly   350 SLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPA 414
            :|.||:|..|.:.||...:|.:::.:..|.|..|.:..:....|.|:..|.||:|....:.::||
  Rat   243 NLSTLTLSGNLLESLPPALFLHVSCVTRLTLFENPLEELPEVLFGEMAGLRELWLNGTHLRTLPA 307

  Fly   415 DLFLNVSALTRLTLFSNN-LTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDS 478
            ..|.|:|.|..|.|..|. |:.|....|.||..|::|.|:.|.|:.....|...|.:|.::.:..
  Rat   308 AAFRNLSGLQTLGLTRNPLLSALPRGMFHGLTELRVLALHTNALEELPEDALRGLGRLRQVSLRH 372

  Fly   479 NKLMFLPHGALHGLKNLVAVKLD------------------------KNPWHCDCRALYLARWIR 519
            |:|..||......|.:||.|:|:                        .|||.|||......:|:|
  Rat   373 NRLRALPRTLFRNLSSLVTVQLEHNQLKTLPGDVFAALPQLTRVLLGHNPWLCDCGLWPFLQWLR 437

  Fly   520 EFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDLCDG-QWASMLSLSPRLPVRKHQISTP 577
            ..:..|...:.|.|.||.....     |.:.:|..| ||.......|..|..::.:..|
  Rat   438 HHLELLGRDEPPQCNGPESRAS-----LTFWELLQGDQWCPDPRGLPPDPPTENALKAP 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	19/82 (23%)
		leucine-rich repeat	187..206	CDD:275380	5/18 (28%)
		LRR_RI	<201..386	CDD:238064	60/208 (29%)
		leucine-rich repeat	207..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..254	CDD:275380	10/46 (22%)
		LRR_8	253..313	CDD:290566	19/59 (32%)
		leucine-rich repeat	255..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	7/22 (32%)
		LRR_8	303..361	CDD:290566	19/57 (33%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		LRR_8	349..407	CDD:290566	17/57 (30%)
		LRR_4	350..390	CDD:289563	11/39 (28%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..398	CDD:275380	5/22 (23%)
		LRR_8	398..>443	CDD:290566	16/45 (36%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		leucine-rich repeat	423..443	CDD:275380	7/20 (35%)
		leucine-rich repeat	471..494	CDD:275380	6/22 (27%)
		LRRCT	503..554	CDD:214507	15/50 (30%)
Gp5	NP_036927.2	LRR_8	<64..110	CDD:404697	14/45 (31%)
		LRR 1	75..96		5/20 (25%)
		leucine-rich repeat	76..99	CDD:275380	6/22 (27%)
		LRR 2	99..120		3/20 (15%)
		leucine-rich repeat	100..123	CDD:275380	3/22 (14%)
		PRK15370	<103..>422	CDD:185268	86/318 (27%)
		LRR 3	123..144		5/20 (25%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		LRR 4	147..168		8/20 (40%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR 5	171..193		6/21 (29%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		LRR 6	195..216		7/20 (35%)
		leucine-rich repeat	196..219	CDD:275380	8/22 (36%)
		LRR 7	219..240		5/20 (25%)
		leucine-rich repeat	220..243	CDD:275380	6/22 (27%)
		LRR 8	243..264		8/20 (40%)
		leucine-rich repeat	244..267	CDD:275380	8/22 (36%)
		LRR 9	267..288		4/20 (20%)
		leucine-rich repeat	268..291	CDD:275380	5/22 (23%)
		LRR 10	291..312		7/20 (35%)
		leucine-rich repeat	292..315	CDD:275380	8/22 (36%)
		LRR 11	315..337		7/21 (33%)
		leucine-rich repeat	316..338	CDD:275380	7/21 (33%)
		LRR 12	340..361		6/20 (30%)
		leucine-rich repeat	341..364	CDD:275380	7/22 (32%)
		LRR 13	364..385		5/20 (25%)
		leucine-rich repeat	365..388	CDD:275380	6/22 (27%)
		LRR 14	388..409		4/20 (20%)
		leucine-rich repeat	389..410	CDD:275380	4/20 (20%)
		PCC	394..>458	CDD:188093	14/63 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	474..499		3/18 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3885
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D595054at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm63545
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.970