DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Lrrc15

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_659551.1 Gene:Lrrc15 / 246296 RGDID:70551 Length:578 Species:Rattus norvegicus


Alignment Length:454 Identity:132/454 - (29%)
Similarity:206/454 - (45%) Gaps:50/454 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 SRLRSVEQPVWHLATGSQI-------EWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPMN- 182
            ||...||      .||::|       .||            ..|....||::..:|....:.:: 
  Rat    32 SRASQVE------CTGARIVAMPTPLPWN------------AMSLQVVNTHITELPENLFLNISA 78

  Fly   183 MVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHR 247
            ::.:.:.:|.|||:....||.|..|:.|.:::|.|..||..:|||:::|..|.:.||||..|...
  Rat    79 LIALKMEKNELSTIMPGAFRNLGSLRYLSLANNKLRMLPIRVFQDVNNLESLLLSNNQLVQIQPA 143

  Fly   248 TFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNK 312
            .|.:..||..|.|..|.:..:||..|.|...||.:|:..|...:..|.|.:....|:.|.:..|:
  Rat   144 QFSQFSNLRELQLHGNNLESIPEEAFDHLVGLTKLNLGRNSFTHLSPRLFQHLGNLQVLRLHENR 208

  Fly   313 ISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVT 377
            :|::..|:...|..|:.|....|||..:....|...|:|:.|.|.||.||.|...||..|..|..
  Rat   209 LSDIPMGTFDALGNLQELALQENQIGTLSPGLFHNNRNLQRLYLSNNHISQLPPGIFMQLPQLNK 273

  Fly   378 LDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQ 442
            |.|..|.:..:....|..:.||.||:|..|.::|:..:.|.:::.|..|.|..|.||.:....|.
  Rat   274 LTLFGNSLRELSPGVFGPMPNLRELWLYNNHITSLADNTFSHLNQLQVLILSHNQLTYISPGAFN 338

  Fly   443 GLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKL------MF------------------ 483
            ||.||:.|.|:.|.|::.|:..|..|:.|:.:.:.||:|      :|                  
  Rat   339 GLTNLRELSLHTNALQDLDSNVFRSLANLQNISLQSNRLRQLPGSIFANVNGLTTIQLQNNNLEN 403

  Fly   484 LPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLL 547
            ||.|....|.||..::|..|||.||...|.|..|:.....:|.....|:|..|.::.|..:.::
  Rat   404 LPLGIFDHLVNLCELRLYDNPWRCDSDILPLHNWLLLNRARLGTDTLPVCSSPANVRGQSLVII 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566 20/59 (34%)
leucine-rich repeat 187..206 CDD:275380 7/18 (39%)
LRR_RI <201..386 CDD:238064 63/184 (34%)
leucine-rich repeat 207..230 CDD:275380 9/22 (41%)
leucine-rich repeat 231..254 CDD:275380 8/22 (36%)
LRR_8 253..313 CDD:290566 18/59 (31%)
leucine-rich repeat 255..278 CDD:275380 8/22 (36%)
leucine-rich repeat 279..302 CDD:275380 6/22 (27%)
LRR_8 303..361 CDD:290566 18/57 (32%)
leucine-rich repeat 303..326 CDD:275380 6/22 (27%)
leucine-rich repeat 327..350 CDD:275380 6/22 (27%)
LRR_8 349..407 CDD:290566 22/57 (39%)
LRR_4 350..390 CDD:289563 15/39 (38%)
leucine-rich repeat 351..374 CDD:275380 11/22 (50%)
leucine-rich repeat 375..398 CDD:275380 5/22 (23%)
LRR_8 398..>443 CDD:290566 15/44 (34%)
leucine-rich repeat 399..422 CDD:275380 7/22 (32%)
leucine-rich repeat 423..443 CDD:275380 7/19 (37%)
leucine-rich repeat 471..494 CDD:275380 9/46 (20%)
LRRCT 503..554 CDD:214507 13/45 (29%)
Lrrc15NP_659551.1 LRR_8 54..113 CDD:290566 15/70 (21%)
LRR 1 54..75 5/32 (16%)
LRR 2 78..99 5/20 (25%)
leucine-rich repeat 79..102 CDD:275380 7/22 (32%)
LRR_RI <94..303 CDD:238064 69/208 (33%)
LRR_8 102..161 CDD:290566 22/58 (38%)
LRR 3 102..123 7/20 (35%)
leucine-rich repeat 103..126 CDD:275380 9/22 (41%)
LRR 4 126..147 8/20 (40%)
leucine-rich repeat 127..150 CDD:275380 8/22 (36%)
LRR_8 149..209 CDD:290566 18/59 (31%)
LRR 5 150..171 8/20 (40%)
leucine-rich repeat 151..174 CDD:275380 8/22 (36%)
LRR 6 174..195 6/20 (30%)
leucine-rich repeat 175..198 CDD:275380 6/22 (27%)
LRR_8 198..257 CDD:290566 18/58 (31%)
LRR 7 198..219 5/20 (25%)
leucine-rich repeat 199..222 CDD:275380 6/22 (27%)
LRR 8 222..243 6/20 (30%)
leucine-rich repeat 223..246 CDD:275380 6/22 (27%)
LRR_8 245..305 CDD:290566 23/59 (39%)
LRR 9 246..267 10/20 (50%)
leucine-rich repeat 247..270 CDD:275380 11/22 (50%)
LRR 10 270..291 5/20 (25%)
leucine-rich repeat 271..294 CDD:275380 5/22 (23%)
LRR_8 293..353 CDD:290566 22/59 (37%)
LRR 11 294..315 8/20 (40%)
leucine-rich repeat 295..318 CDD:275380 7/22 (32%)
LRR_4 318..358 CDD:289563 15/39 (38%)
LRR 12 318..339 7/20 (35%)
leucine-rich repeat 319..342 CDD:275380 9/22 (41%)
LRR 13 342..363 8/20 (40%)
leucine-rich repeat 343..364 CDD:275380 7/20 (35%)
LRR_8 366..424 CDD:290566 12/57 (21%)
LRR 14 366..387 5/20 (25%)
leucine-rich repeat 367..387 CDD:275380 5/19 (26%)
LRR 15 390..411 3/20 (15%)
leucine-rich repeat 391..412 CDD:275380 3/20 (15%)
TPKR_C2 423..>462 CDD:301599 12/38 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 476..500
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BET7
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 181 1.000 Inparanoid score I3885
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D595054at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm63545
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.870

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