Protein Alignment CG7509 and Tsku

DIOPT Version :10

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001019790.1
• Gene: Tsku / 244152
• MGIID: 2443855
• Length: 354
• Species: Mus musculus
• Alignment Length: 431
• Identity: 111/431 - (25%)
• Similarity: 168/431 - (38%)
• Gaps: 121/431 - (28%)

  Fly   138 LATGSQIEWNHCTSGVCRCNPDT----KSFT-----CWNTNLKSVPVTQVIPMNMVNIDLSRNIL 193
            ||.|.......|..| |:|..:|    .||:     |.:.....|||.  ||::..::|||.|.|
Mouse    10 LAVGRVQTTRPCFPG-CQCEEETFGLFDSFSLIRVDCSSLGPHIVPVP--IPLDTAHLDLSSNRL 71

  Fly   194 STLHKDTFR--GLTVLKELDISHNVL-DFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNL 255
            .|:::....  |.|.|..||:|:|:| ..:|                         ..|.:||.|
Mouse    72 ETVNESVLAGPGYTTLAGLDLSYNLLTSIMP-------------------------SAFSRLRYL 111

  Fly   256 NILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLL--RDQLMLEELDMSRNKISEL-- 316
            ..||||.|.:..||..|| .:..|:.||:..|:::....:..  ..|.....:|:|.|.|..|
Mouse   112 ESLDLSHNGLAALPAEIF-TSSPLSDINLSHNRLREVSISAFTTHSQGRALHVDLSHNLIHRLLP 175

  Fly   317 --SSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLD 379
              :..|:...| :::|:..||:...:.|        ||.|.|   |..||.|
Mouse   176 HPARASLPAPT-IQSLNLSWNRFRAVPD--------LRDLPL---RYLSLDG------------- 215

  Fly   380 LTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFS-NNLTTLEADDFQG 443
                                       |.:::|..|.|:.::.||.|:|.| ..:..|....|:.
Mouse   216 ---------------------------NPLATINPDAFMGLAGLTHLSLASLQGILHLPPHGFRE 253

  Fly   444 LNNLKILLLNNN-ILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHC 507
            |..|::|.|:.| .||...|..|..|..|::|.:..:.|:.||...||.|..|.:|.:.::   .
Mouse   254 LPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLLHHLPALQSVSVGQD---V 315

  Fly   508 DCRALYLARWIRE------------FVLKLWDGQQPMCRGP 536
            .||     |.:||            .||...|.|:...|||
Mouse   316 QCR-----RLVREGAYHRQPGSSPKVVLHCGDTQESAARGP 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR	185..>437	CDD:443914	61/261 (23%)
		leucine-rich repeat	187..206	CDD:275380	7/20 (35%)
		leucine-rich repeat	207..230	CDD:275380	7/23 (30%)
		leucine-rich repeat	231..254	CDD:275380	2/22 (9%)
		leucine-rich repeat	255..278	CDD:275380	10/22 (45%)
		leucine-rich repeat	279..302	CDD:275380	5/24 (21%)
		leucine-rich repeat	303..326	CDD:275380	6/26 (23%)
		leucine-rich repeat	327..350	CDD:275380	4/22 (18%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..398	CDD:275380	0/22 (0%)
		leucine-rich repeat	399..422	CDD:275380	4/22 (18%)
		leucine-rich repeat	423..443	CDD:275380	7/20 (35%)
		leucine-rich repeat	471..494	CDD:275380	8/22 (36%)
		PCC	476..>561	CDD:188093	20/73 (27%)
Tsku	NP_001019790.1	LRR 1	60..81		6/20 (30%)
		leucine-rich repeat	63..86	CDD:275380	7/22 (32%)
		LRR	<85..>300	CDD:443914	71/292 (24%)
		LRR 2	86..107		8/45 (18%)
		leucine-rich repeat	87..110	CDD:275380	9/47 (19%)
		LRR 3	110..131		10/21 (48%)
		leucine-rich repeat	111..132	CDD:275380	10/21 (48%)
		LRR 4	133..154		4/20 (20%)
		leucine-rich repeat	134..186	CDD:275380	11/51 (22%)
		leucine-rich repeat	158..182	CDD:275380	5/23 (22%)
		LRR 5	160..180		5/19 (26%)
		LRR 6	186..207		7/29 (24%)
		leucine-rich repeat	187..205	CDD:275380	5/25 (20%)
		leucine-rich repeat	208..231	CDD:275380	9/65 (14%)
		LRR 7	208..228		9/62 (15%)
		LRR 8	231..253		7/21 (33%)
		leucine-rich repeat	232..256	CDD:275380	8/23 (35%)
		LRR 9	256..277		7/20 (35%)
		leucine-rich repeat	257..281	CDD:275380	9/23 (39%)
		LRR 10	281..302		6/20 (30%)
		leucine-rich repeat	282..305	CDD:275380	8/22 (36%)