DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and Lrrc26

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_666229.1	Gene:	Lrrc26 / 227618	MGIID:	2385129	Length:	331	Species:	Mus musculus

Alignment Length:	186	Identity:	56/186 - (30%)
Similarity:	81/186 - (43%)	Gaps:	24/186 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 LRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPAD 415
            :|:|.|.:||:|:|....|.|...|:.|||..||:..:...||..|..|..|.|..|.:.::|..
Mouse    73 VRSLLLDHNRVSALPPGAFANAGALLYLDLRENRLRSVHARAFWGLGVLQWLDLSSNQLETLPPG 137

  Fly   416 LFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNK 480
            .|..:.||:.|:|..|.|..||......|..|::|.|.:|.|...:|.....|..|:.||
Mouse   138 TFAPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSAIEAGLLNNLPALDVLR----- 197

  Fly   481 LMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGP 536
                    |||           |||.|:|....|..|:|:......:.:..:|..|
Mouse   198 --------LHG-----------NPWTCNCALRPLCTWLRKHPRPASETETLLCVSP 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566
		leucine-rich repeat	187..206	CDD:275380
		LRR_RI	<201..386	CDD:238064	15/34 (44%)
		leucine-rich repeat	207..230	CDD:275380
		leucine-rich repeat	231..254	CDD:275380
		LRR_8	253..313	CDD:290566
		leucine-rich repeat	255..278	CDD:275380
		leucine-rich repeat	279..302	CDD:275380
		LRR_8	303..361	CDD:290566	4/9 (44%)
		leucine-rich repeat	303..326	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		LRR_8	349..407	CDD:290566	21/55 (38%)
		LRR_4	350..390	CDD:289563	15/38 (39%)
		leucine-rich repeat	351..374	CDD:275380	9/22 (41%)
		leucine-rich repeat	375..398	CDD:275380	9/22 (41%)
		LRR_8	398..>443	CDD:290566	14/44 (32%)
		leucine-rich repeat	399..422	CDD:275380	6/22 (27%)
		leucine-rich repeat	423..443	CDD:275380	7/19 (37%)
		leucine-rich repeat	471..494	CDD:275380	6/22 (27%)
		LRRCT	503..554	CDD:214507	10/34 (29%)
Lrrc26	NP_666229.1	LRR_8	72..131	CDD:290566	22/57 (39%)
		LRR 1	72..93		8/19 (42%)
		leucine-rich repeat	73..96	CDD:275380	9/22 (41%)
		LRR 2	96..117		8/20 (40%)
		leucine-rich repeat	97..120	CDD:275380	9/22 (41%)
		LRR	118..141	CDD:197688	7/22 (32%)
		LRR 3	120..141		6/20 (30%)
		LRR_8	121..179	CDD:290566	19/57 (33%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR 4	144..165		8/20 (40%)
		leucine-rich repeat	145..168	CDD:275380	8/22 (36%)
		LRR 5	168..191		6/22 (27%)
		LRR_4	169..204	CDD:289563	15/58 (26%)
		leucine-rich repeat	169..192	CDD:275380	7/22 (32%)
		TPKR_C2	201..244	CDD:301599	10/34 (29%)
		leucine-rich repeat	236..255	CDD:275380
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	310..331
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930