Protein Alignment CG7509 and sym-1

DIOPT Version :10

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_510426.1
• Gene: sym-1 / 181555
• WormBaseID: WBGene00006366
• Length: 680
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 127/554 - (22%)
• Similarity: 214/554 - (38%)
• Gaps: 128/554 - (23%)

  Fly    98 DGDVNGGEINAMSHLANFDLVKRVRQIESRLRSVEQPVWHLATGSQIEWNHCTSGVCRCNPDTKS 162
            |..|.|..|....|              ..||.||:    |:|.:.:|.....
 Worm    32 DSTVEGPVIKCSGH--------------DGLRMVEK----LSTTTTMEVRELA------------ 66

  Fly   163 FTCWNTNLKSVPVTQVIP-----MNMVNIDLSRNILSTLHKDTFRGL-TVLKELDISHNVLDFLP 221
                   |::..:.:|.|     :.:..:.||.|.:..:|...|.|| .|::||.:|.|.|..:|
 Worm    67 -------LENADIIEVGPKAFKTLRIKKLILSNNRIEKIHDHAFTGLENVMQELSLSENNLKEVP 124

  Fly   222 FDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCD 286
            ......|..|.:|.::.|::|:|..:.|..:.:|..::|..|:|..:....|.:.
 Worm   125 TSALAGLRVLNILSLKCNKIENITTKAFVNMTSLIDVNLGCNQICSMAADTFANV---------- 179

  Fly   287 NQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSL 351
                         ::.|:.|.:..|.::|..|.::|.:..|..|...:|:|..|..:.|..|.||
 Worm   180 -------------KMSLQNLILDNNCMTEFPSKAVRNMNNLIALHIKYNKINAIRQNDFVNLTSL 231

  Fly   352 RTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADL 416
            ..|||:.|.||.:.|....|..||..|.|..|.:..:|.....:...|..|.|..|:.:.|..::
 Worm   232 SMLSLNGNNISEIKGGALQNTPNLHYLYLNENNLQTLDNGVLEQFKQLQVLDLSFNNFTDITKEM 296

  Fly   417 FLNVSALTRLTLFSNNLTTLEADDFQGL--------NN---------------LKILLLNNNILK 458
            |..:.::..|.|.||.::.:....|.|.        ||               |:::.|:||.::
 Worm   297 FEGLESIQHLNLDSNRISAVAPGAFAGTPLLLLWLPNNCLTEVSQQTLKGAPFLRMVSLSNNNIR 361

  Fly   459 NFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYL-----ARWI 518
            .....:|:.|..|..|.:.:||:|.|.:.:|.|.:|| ||:|.:||..|.....::     |.|:
 Worm   362 EVHELSFDHLPNLHTLDLANNKIMSLQNKSLSGPENL-AVRLQENPVVCVKNGFHVLNSGEAIWL 425

  Fly   519 REFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDLCDGQW-ASMLSLSPRL---PVRKHQISTPMN 579
            ..                           ..:.:|.|:| |....|.|:.   |:|....|..:.
 Worm   426 TN---------------------------EANTICKGEWQAQTADLCPKAQPRPIRPVCCSNEIT 463

  Fly   580 YTDYFNLYLKHIYNGTTDEELKEADITSVSIKKV 613
            .|.........:...||.||.||.  |:.:.:||
 Worm   464 TTTTTTTTTTTLAPTTTTEEEKEE--TTETTEKV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR	185..>437	CDD:443914	65/252 (26%)
		leucine-rich repeat	187..206	CDD:275380	7/19 (37%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		leucine-rich repeat	255..278	CDD:275380	5/22 (23%)
		leucine-rich repeat	279..302	CDD:275380	0/22 (0%)
		leucine-rich repeat	303..326	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	7/22 (32%)
		leucine-rich repeat	351..374	CDD:275380	9/22 (41%)
		leucine-rich repeat	375..398	CDD:275380	5/22 (23%)
		leucine-rich repeat	399..422	CDD:275380	6/22 (27%)
		leucine-rich repeat	423..443	CDD:275380	5/19 (26%)
		leucine-rich repeat	471..494	CDD:275380	8/22 (36%)
		PCC	476..>561	CDD:188093	20/90 (22%)
sym-1	NP_510426.1	leucine-rich repeat	62..81	CDD:275380	3/37 (8%)
		LRR	<84..408	CDD:443914	90/347 (26%)
		leucine-rich repeat	86..108	CDD:275380	7/21 (33%)
		leucine-rich repeat	110..133	CDD:275380	7/22 (32%)
		leucine-rich repeat	134..157	CDD:275380	6/22 (27%)
		leucine-rich repeat	158..182	CDD:275380	5/46 (11%)
		leucine-rich repeat	183..206	CDD:275380	6/22 (27%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		leucine-rich repeat	231..254	CDD:275380	9/22 (41%)
		leucine-rich repeat	255..278	CDD:275380	5/22 (23%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		leucine-rich repeat	303..323	CDD:275380	5/19 (26%)
		leucine-rich repeat	350..373	CDD:275380	6/22 (27%)
		leucine-rich repeat	374..394	CDD:275380	7/19 (37%)
		leucine-rich repeat	399..410	CDD:275378	5/10 (50%)