Protein Alignment CG7509 and let-4

DIOPT Version :9

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_510425.2
• Gene: let-4 / 181554
• WormBaseID: WBGene00002282
• Length: 773
• Species: Caenorhabditis elegans
• Alignment Length: 383
• Identity: 109/383 - (28%)
• Similarity: 175/383 - (45%)
• Gaps: 46/383 - (12%)

  Fly   168 TNLKSVPVTQVIPMNMV----------------NIDLSRNILSTLHKDTFRGLT-VLKELDISHN 215
            ||...|.:.|.:.||..                .:|||:|.:..:....|.|:. ||:|:.::||
 Worm    56 TNQAQVGLIQSLTMNQAELVELPPNFFSGLFIRRLDLSQNKIKKIDDAAFAGINPVLEEVVLNHN 120

  Fly   216 VLDFLPFDLFQDLDSLLVLRIQNNQLEDI-DHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQR- 278
            :::.:|......|.:||.|.:.||.:.:| :...|..|..|..::|..|:|..:..|.|.:.:.
 Worm   121 LIEKVPAAALAGLPNLLRLDLSNNSIVEIQEQEIFPNLNKLYDINLGSNKIFSIHTSTFQNVKNS 185

  Fly   279 LTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDD 343
            :..||:..|.:...|.:.:|....|:.|.:.:|:|.:|.:.:...|..|..|:...|||.:::..
 Worm   186 IQTINLGHNNMTAVPSSAIRGLKQLQSLHLHKNRIEQLDALNFLNLPVLNLLNLAGNQIHELNRQ 250

  Fly   344 FFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNS 408
            .|..:.|||.|.|..|:|:.|:...|.....|..||||.|.|..|..|:...|..|.:|:|..|.
 Worm   251 AFLNVPSLRYLYLSGNKITKLTAYQFQTFEQLEMLDLTNNEIGAIPANSLSGLKQLRQLYLAHNK 315

  Fly   409 MSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEP------ 467
            :|:|.::.|.| |::..|.|.||.|.||.|....||.||:.:...:|.:|..:..||..
 Worm   316 ISNISSNAFTN-SSIVVLVLSSNELKTLTAGIISGLPNLQQVSFRDNQIKTINRNAFYDAASLVM 379

  Fly   468 ----------------LSQLEKLRID--SNKLMFLPHGALHGLKNLVAVKLDKNPWHC 507
                            |:||..|.:|  .|||...|:.|.:.....|.:|  :||..|
 Worm   380 LDLAKNQLTEIAPTTFLAQLNLLLVDLSENKLPKTPYSAFNSRVGTVLLK--ENPLVC 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	19/75 (25%)
		leucine-rich repeat	187..206	CDD:275380	6/19 (32%)
		LRR_RI	<201..386	CDD:238064	55/187 (29%)
		leucine-rich repeat	207..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..254	CDD:275380	8/23 (35%)
		LRR_8	253..313	CDD:290566	14/60 (23%)
		leucine-rich repeat	255..278	CDD:275380	6/22 (27%)
		leucine-rich repeat	279..302	CDD:275380	5/22 (23%)
		LRR_8	303..361	CDD:290566	18/57 (32%)
		leucine-rich repeat	303..326	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		LRR_8	349..407	CDD:290566	22/57 (39%)
		LRR_4	350..390	CDD:289563	17/39 (44%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..398	CDD:275380	10/22 (45%)
		LRR_8	398..>443	CDD:290566	17/44 (39%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		leucine-rich repeat	423..443	CDD:275380	8/19 (42%)
		leucine-rich repeat	471..494	CDD:275380	8/24 (33%)
		LRRCT	503..554	CDD:214507	3/5 (60%)
let-4	NP_510425.2	leucine-rich repeat	66..86	CDD:275380	2/19 (11%)
		LRR_RI	<71..275	CDD:238064	52/203 (26%)
		LRR_8	88..146	CDD:290566	18/57 (32%)
		leucine-rich repeat	88..111	CDD:275380	6/22 (27%)
		leucine-rich repeat	112..135	CDD:275380	6/22 (27%)
		leucine-rich repeat	136..160	CDD:275380	8/23 (35%)
		LRR_8	156..220	CDD:290566	15/63 (24%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		leucine-rich repeat	186..209	CDD:275380	5/22 (23%)
		leucine-rich repeat	210..257	CDD:275380	12/46 (26%)
		LRR_RI	<250..411	CDD:238064	51/161 (32%)
		LRR_8	256..316	CDD:290566	23/59 (39%)
		leucine-rich repeat	258..281	CDD:275380	8/22 (36%)
		leucine-rich repeat	282..305	CDD:275380	10/22 (45%)
		leucine-rich repeat	306..328	CDD:275380	8/22 (36%)
		LRR_8	327..387	CDD:290566	17/59 (29%)
		leucine-rich repeat	329..350	CDD:275380	8/20 (40%)
		leucine-rich repeat	353..400	CDD:275380	7/46 (15%)
		leucine-rich repeat	356..376	CDD:275380	4/19 (21%)
		leucine-rich repeat	401..419	CDD:275380	6/17 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910