DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Lrrn1

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_032542.1 Gene:Lrrn1 / 16979 MGIID:106038 Length:716 Species:Mus musculus


Alignment Length:427 Identity:104/427 - (24%)
Similarity:175/427 - (40%) Gaps:59/427 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   198 KDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSK 262
            :.|:|..|.   :|.:...|..:|.:|..|...||:.  .||..:.:|.  ..:|.||..||.|:
Mouse    47 QSTYREATT---VDCNDLRLTRIPGNLSSDTQVLLLQ--SNNIAKTVDE--LQQLFNLTELDFSQ 104

  Fly   263 NEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKL 327
            |....:.|....:..:||.:::.:|||.......|:|...|:||.::.|:||.:|:.:...|..|
Mouse   105 NNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYINHNQISTISANAFSGLKNL 169

  Fly   328 KTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNA 392
            ..|....|::..||..:|....:|..|.:..|.:..:....|..|:||.:|.|....::.:.|||
Mouse   170 LRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFRPLSNLRSLVLAGMYLTDVPGNA 234

  Fly   393 FVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQ--------GLNNL-- 447
            .|.|::|..|....|.:..:|......|..|..|.|..|.:..::..||:        |:||:  
Mouse   235 LVGLDSLESLSFYDNKLIKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGE 299

  Fly   448 ----------------KILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLV 496
                            |:...||..|......||..:..||.|.:::|.|..:....:..|.||.
Mouse   300 LVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAVYQKTVESLPNLR 364

  Fly   497 AVKLDKNPWHCDCRALYLARWI--REFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDLCDGQWAS 559
            .:.:..||..|||    :..||  .:..::..:.....|..|.:..|.:|..:...|        
Mouse   365 EISIHSNPLRCDC----VIHWINSNKTNIRFMEPLSMFCAMPPEYRGQQVKEVLIQD-------- 417

  Fly   560 MLSLSPRLPVRKHQISTPMNYTDYFNLYLKHIYNGTT 596
              |....||:..|.     .:.::.|:.:     |||
Mouse   418 --SSEQCLPMISHD-----TFPNHLNMDI-----GTT 442

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566 12/42 (29%)
leucine-rich repeat 187..206 CDD:275380 2/7 (29%)
LRR_RI <201..386 CDD:238064 50/184 (27%)
leucine-rich repeat 207..230 CDD:275380 5/22 (23%)
leucine-rich repeat 231..254 CDD:275380 6/22 (27%)
LRR_8 253..313 CDD:290566 18/59 (31%)
leucine-rich repeat 255..278 CDD:275380 6/22 (27%)
leucine-rich repeat 279..302 CDD:275380 7/22 (32%)
LRR_8 303..361 CDD:290566 17/57 (30%)
leucine-rich repeat 303..326 CDD:275380 8/22 (36%)
leucine-rich repeat 327..350 CDD:275380 6/22 (27%)
LRR_8 349..407 CDD:290566 16/57 (28%)
LRR_4 350..390 CDD:289563 9/39 (23%)
leucine-rich repeat 351..374 CDD:275380 5/22 (23%)
leucine-rich repeat 375..398 CDD:275380 8/22 (36%)
LRR_8 398..>443 CDD:290566 11/52 (21%)
leucine-rich repeat 399..422 CDD:275380 5/22 (23%)
leucine-rich repeat 423..443 CDD:275380 6/27 (22%)
leucine-rich repeat 471..494 CDD:275380 6/22 (27%)
LRRCT 503..554 CDD:214507 12/52 (23%)
Lrrn1NP_032542.1 LRR_RI 11..273 CDD:238064 64/232 (28%)
leucine-rich repeat 54..73 CDD:275380 5/21 (24%)
LRR 1 73..95 6/25 (24%)
leucine-rich repeat 74..96 CDD:275380 6/25 (24%)
LRR 2 96..117 7/20 (35%)
leucine-rich repeat 97..120 CDD:275380 6/22 (27%)
LRR_8 119..179 CDD:290566 18/59 (31%)
LRR 3 120..141 6/20 (30%)
leucine-rich repeat 121..144 CDD:275380 7/22 (32%)
LRR 4 144..165 7/20 (35%)
leucine-rich repeat 145..168 CDD:275380 8/22 (36%)
LRR 5 168..189 6/20 (30%)
leucine-rich repeat 169..192 CDD:275380 6/22 (27%)
LRR 6 192..213 4/20 (20%)
leucine-rich repeat 193..216 CDD:275380 5/22 (23%)
LRR_RI 211..>376 CDD:238064 41/164 (25%)
LRR_8 215..275 CDD:290566 18/59 (31%)
LRR 7 216..237 7/20 (35%)
leucine-rich repeat 217..240 CDD:275380 8/22 (36%)
LRR 8 240..261 4/20 (20%)
leucine-rich repeat 241..264 CDD:275380 5/22 (23%)
LRR_8 263..323 CDD:290566 11/59 (19%)
LRR 9 264..285 6/20 (30%)
leucine-rich repeat 265..288 CDD:275380 6/22 (27%)
leucine-rich repeat 289..313 CDD:275380 3/23 (13%)
LRR_8 312..373 CDD:290566 15/60 (25%)
leucine-rich repeat 314..335 CDD:275380 6/20 (30%)
leucine-rich repeat 339..362 CDD:275378 6/22 (27%)
leucine-rich repeat 363..375 CDD:275378 3/11 (27%)
LRRCT 371..419 CDD:214507 12/61 (20%)
I-set 429..516 CDD:254352 4/24 (17%)
Ig 431..516 CDD:299845 4/17 (24%)
fn3 531..600 CDD:278470
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 692..716
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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