Protein Alignment CG7509 and ADGRA3

DIOPT Version :9

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_660333.2
• Gene: ADGRA3 / 166647
• HGNCID: 13839
• Length: 1321
• Species: Homo sapiens
• Alignment Length: 180
• Identity: 54/180 - (30%)
• Similarity: 82/180 - (45%)
• Gaps: 28/180 - (15%)

  Fly   376 VTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADD 440
            |||.|:.|:||.:...:|..|:.|..|.|..|.:|||....|..:|:|.||.|.:|.:..|.||.
Human    84 VTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLDLTNNRIGCLNADI 148

  Fly   441 FQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPW 505
            |:||.||..|.|:.|:..:.....|:.|:.|..|...:..|:
Human   149 FRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLL----------------------- 190

  Fly   506 HCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDL-CD 554
             |||..|::.||::|..:.:.|.:   |..|..|....|..::.:.| ||
Human   191 -CDCNILWMHRWVKEKNITVRDTR---CVYPKSLQAQPVTGVKQELLTCD 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566
		leucine-rich repeat	187..206	CDD:275380
		LRR_RI	<201..386	CDD:238064	5/9 (56%)
		leucine-rich repeat	207..230	CDD:275380
		leucine-rich repeat	231..254	CDD:275380
		LRR_8	253..313	CDD:290566
		leucine-rich repeat	255..278	CDD:275380
		leucine-rich repeat	279..302	CDD:275380
		LRR_8	303..361	CDD:290566
		leucine-rich repeat	303..326	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		LRR_8	349..407	CDD:290566	12/30 (40%)
		LRR_4	350..390	CDD:289563	7/13 (54%)
		leucine-rich repeat	351..374	CDD:275380
		leucine-rich repeat	375..398	CDD:275380	9/21 (43%)
		LRR_8	398..>443	CDD:290566	18/44 (41%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		leucine-rich repeat	423..443	CDD:275380	9/19 (47%)
		leucine-rich repeat	471..494	CDD:275380	3/22 (14%)
		LRRCT	503..554	CDD:214507	13/51 (25%)
ADGRA3	NP_660333.2	LRR_RI	<70..>182	CDD:238064	37/97 (38%)
		LRR 1	82..103		8/18 (44%)
		leucine-rich repeat	83..106	CDD:275378	9/21 (43%)
		LRR_8	85..141	CDD:290566	22/55 (40%)
		LRR 2	106..127		8/20 (40%)
		LRR_4	107..146	CDD:289563	15/38 (39%)
		leucine-rich repeat	107..130	CDD:275378	8/22 (36%)
		LRR_8	129..182	CDD:290566	20/52 (38%)
		LRR 3	130..151		9/20 (45%)
		leucine-rich repeat	131..154	CDD:275378	11/22 (50%)
		LRR 4	154..175		6/20 (30%)
		leucine-rich repeat	155..178	CDD:275378	6/22 (27%)
		LRRCT	189..>223	CDD:214507	12/60 (20%)
		IG_like	249..341	CDD:214653
		Ig	262..337	CDD:143165
		HRM	<363..416	CDD:280888
		LRR 5	594..620
		GPS	704..743	CDD:280071
		7tm_4	796..>945	CDD:304433
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1073..1094
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1198..1219
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1231..1265
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1294..1321
		PDZ-binding. /evidence=ECO:0000255	1319..1321

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910