Protein Alignment CG7509 and CHADL

DIOPT Version :10

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: XP_054181131.1
• Gene: CHADL / 150356
• HGNCID: 25165
• Length: 771
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 111/441 - (25%)
• Similarity: 162/441 - (36%)
• Gaps: 89/441 - (20%)

  Fly   138 LATGSQIEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPMNMVNIDLSRNILSTLHKDTFR 202
            ||...|.....|.. .|.|:...:...|...||..||  ..||.....:||..|:|..:....|:
Human    22 LAPARQAAAQRCPQ-ACICDNSRRHVACRYQNLTEVP--DAIPELTQRLDLQGNLLKVIPAAAFQ 83

  Fly   203 GLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGM 267
            |:..|..||:.|..::.:....|:.|..||:|.:.:|.|.::.......|.:|..|:|..|.:..
Human    84 GVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEE 148

  Fly   268 LPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDF 332
            |....|.....|..:|:..|.:...|....:..|.:..|.:|.|.:|.|:..::
Human   149 LRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEAL----------- 202

  Fly   333 GWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELN 397
                         |||.:||.||||:|.:.:|.|.:.:
Human   203 -------------AGLPALRRLSLHHNELQALPGPVLS--------------------------- 227

  Fly   398 NLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDA 462
                                 ....|.||.|..|.||....:|...|..|:.|||:...|:....
Human   228 ---------------------QARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGP 271

  Fly   463 RAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWD 527
            |||....:|..|.:..|:|..||  .|.|...|..::|..||..|.|:|..|..|:....::. |
Human   272 RAFAHCPRLHTLDLRGNQLDTLP--PLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARARVRS-D 333

  Fly   528 GQQPMCRGPGDLGGHEVGLLRYDDL-CDGQWA-------SMLSLSPRLPVR 570
            |   .|:||..|.|..:..||..|| |.|..|       ......||.|.|
Human   334 G---ACQGPRRLRGEALDALRPWDLRCPGDAAQEEEELEERAVAGPRAPPR 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR	185..>437	CDD:443914	53/251 (21%)
		leucine-rich repeat	187..206	CDD:275380	6/18 (33%)
		leucine-rich repeat	207..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		leucine-rich repeat	255..278	CDD:275380	6/22 (27%)
		leucine-rich repeat	279..302	CDD:275380	4/22 (18%)
		leucine-rich repeat	303..326	CDD:275380	5/22 (23%)
		leucine-rich repeat	327..350	CDD:275380	3/22 (14%)
		leucine-rich repeat	351..374	CDD:275380	9/22 (41%)
		leucine-rich repeat	375..398	CDD:275380	0/22 (0%)
		leucine-rich repeat	399..422	CDD:275380	0/22 (0%)
		leucine-rich repeat	423..443	CDD:275380	8/19 (42%)
		leucine-rich repeat	471..494	CDD:275380	8/22 (36%)
		PCC	476..>561	CDD:188093	29/92 (32%)
CHADL	XP_054181131.1	LRRNT	33..65	CDD:214470	10/34 (29%)
		leucine-rich repeat	44..62	CDD:275380	6/19 (32%)
		leucine-rich repeat	64..87	CDD:275380	6/22 (27%)
		LRR_8	65..146	CDD:404697	22/80 (28%)
		leucine-rich repeat	88..135	CDD:275380	12/46 (26%)
		LRR	<128..>312	CDD:443914	57/257 (22%)
		leucine-rich repeat	136..159	CDD:275380	6/22 (27%)
		leucine-rich repeat	160..183	CDD:275380	4/22 (18%)
		leucine-rich repeat	184..207	CDD:275380	8/46 (17%)
		leucine-rich repeat	208..231	CDD:275380	9/70 (13%)
		leucine-rich repeat	232..255	CDD:275380	9/22 (41%)
		leucine-rich repeat	256..279	CDD:275380	8/22 (36%)
		LRRNT	395..429	CDD:214470
		leucine-rich repeat	410..426	CDD:275380
		leucine-rich repeat	427..450	CDD:275380
		LRR	<445..>677	CDD:443914
		leucine-rich repeat	451..474	CDD:275380
		leucine-rich repeat	475..498	CDD:275380
		leucine-rich repeat	499..522	CDD:275380
		leucine-rich repeat	523..546	CDD:275380
		leucine-rich repeat	547..570	CDD:275380
		leucine-rich repeat	571..594	CDD:275380
		leucine-rich repeat	595..619	CDD:275380
		leucine-rich repeat	620..644	CDD:275380
		LRRCT	675..723	CDD:214507