DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and AgaP_AGAP007846

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_317652.4	Gene:	AgaP_AGAP007846 / 1278113	VectorBaseID:	AGAP007846	Length:	961	Species:	Anopheles gambiae

Alignment Length:	368	Identity:	97/368 - (26%)
Similarity:	154/368 - (41%)	Gaps:	67/368 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 KELDISHNVLDFLPFDLFQDLDS------LLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIG 266
            :||.:..:.:|| |. |.:.||.      |.:|.:.|:.:|.::...|..|: |:.:.||..::.
Mosquito    52 QELSVQCDQVDF-PV-LVEALDKYARATPLDLLYVNNSTIEQLEGGLFVNLK-LHNVQLSSCKMR 113

  Fly   267 MLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLD 331
            .:.:..|.                       ..:.:|:.|::..|.:.|:...:::.||.|..||
Mosquito   114 RIDDKAFQ-----------------------GQEAVLKNLNLQDNLLEEVPIRALKPLTILNLLD 155

  Fly   332 FGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNL-ANLVTLDLTTNRISHIDGNAFVE 395
            ...|::..:.:|.|||||.|.||.|.:|.: :|:...|..| |:|..|:|...:...:. .|...
Mosquito   156 LSKNRLHSVPNDAFAGLRKLSTLKLSDNNV-TLAPFAFRGLEASLKNLNLKGTKQKRVP-EAVRG 218

  Fly   396 LNNLNELFLGQNSMSSIPADL----FLNVSALTRLTLFSNNLTTLEADDFQGL-NNLKILLLNNN 455
            |..|..|.|.||.:..:|...    |..:.|||.|.|..|.:.:|....|.|: ..|..|.|.||
Mosquito   219 LRTLAFLDLSQNGIRELPGGAGVKSFDGLDALTALNLERNLIQSLGETAFSGVRKTLSSLSLLNN 283

  Fly   456 ILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNP---------------- 504
            :|..|...|...|.:|..|.|..|.|..||..|..|...:..:.||.||
Mosquito   284 LLAEFPVGAIHSLRELRVLDIGFNLLTALPETAFRGNPAVTLLALDGNPLPTVPEKALAHLNRTL 348

  Fly   505 ---------WHCDCRALYLARWIREFVLKLWDGQQ--PMCRGP 536
                     .||||:..::|.|||...|::...::  ..|..|
Mosquito   349 RGLSLGGRFLHCDCKLRWVAEWIRNGDLQVTSRERNPQFCGSP 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	11/38 (29%)
		leucine-rich repeat	187..206	CDD:275380
		LRR_RI	<201..386	CDD:238064	46/184 (25%)
		leucine-rich repeat	207..230	CDD:275380	7/21 (33%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		LRR_8	253..313	CDD:290566	7/59 (12%)
		leucine-rich repeat	255..278	CDD:275380	4/22 (18%)
		leucine-rich repeat	279..302	CDD:275380	0/22 (0%)
		LRR_8	303..361	CDD:290566	21/57 (37%)
		leucine-rich repeat	303..326	CDD:275380	5/22 (23%)
		leucine-rich repeat	327..350	CDD:275380	9/22 (41%)
		LRR_8	349..407	CDD:290566	18/58 (31%)
		LRR_4	350..390	CDD:289563	12/40 (30%)
		leucine-rich repeat	351..374	CDD:275380	8/23 (35%)
		leucine-rich repeat	375..398	CDD:275380	5/22 (23%)
		LRR_8	398..>443	CDD:290566	15/48 (31%)
		leucine-rich repeat	399..422	CDD:275380	7/26 (27%)
		leucine-rich repeat	423..443	CDD:275380	7/19 (37%)
		leucine-rich repeat	471..494	CDD:275380	9/22 (41%)
		LRRCT	503..554	CDD:214507	13/61 (21%)
AgaP_AGAP007846	XP_317652.4	LRR_RI	67..312	CDD:238064	72/270 (27%)
		leucine-rich repeat	79..94	CDD:275380	4/14 (29%)
		leucine-rich repeat	102..125	CDD:275380	4/45 (9%)
		LRR_8	127..185	CDD:290566	21/57 (37%)
		leucine-rich repeat	127..150	CDD:275380	5/22 (23%)
		leucine-rich repeat	151..174	CDD:275380	9/22 (41%)
		LRR_8	173..260	CDD:290566	28/88 (32%)
		leucine-rich repeat	175..198	CDD:275380	8/23 (35%)
		leucine-rich repeat	199..221	CDD:275380	5/22 (23%)
		leucine-rich repeat	222..249	CDD:275380	7/26 (27%)
		LRR_8	250..333	CDD:290566	29/82 (35%)
		leucine-rich repeat	250..273	CDD:275380	8/22 (36%)
		leucine-rich repeat	299..322	CDD:275380	9/22 (41%)
		leucine-rich repeat	323..344	CDD:275380	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910