DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and AgaP_AGAP000360

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_310751.5	Gene:	AgaP_AGAP000360 / 1271896	VectorBaseID:	AGAP000360	Length:	1451	Species:	Anopheles gambiae

Alignment Length:	432	Identity:	117/432 - (27%)
Similarity:	185/432 - (42%)	Gaps:	81/432 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 SGVCRCN--PDTKSFTCWNTNLKSVPVT-QVI--PMNMVNI-DLSRNILSTLHKDTFRGLTV--- 206
            :..|.|.  .|.....|....|.::..| |||  |:..::: |..|:: .||..|.|:|...
Mosquito    81 NSACPCYKFEDGIFLECPGITLAALRSTLQVISSPIQSLSVYDFDRSV-KTLTVDLFQGAAFSTA 144

  Fly   207 --------------------LKELDISHNVLDFL-PFDLFQDLDSLLVLRIQNNQLEDIDHRTFW 250
                                ::.|..||:.|..| |..|......|..|.|.|.:|..:..:...
Mosquito   145 GGSGGGVGLGLDSAAAGNVSIRHLQFSHSSLQQLKPNSLLPLRSHLESLSIINGKLTQVPSKAIV 209

  Fly   251 KLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRD-QLMLEELDMSRNKIS 314
            .|:.|.:|||..||||.| |...:|...|..:|:..|||:..|.|.|.. :..|.|||:|.|::.
Mosquito   210 GLKKLMVLDLDANEIGTL-EDYAFHGLHLVKLNLKSNQIERVPTNALAGLEESLAELDLSENRLR 273

  Fly   315 ELSSGSIRYLTKLKTLDFGWNQIAKI--DD-----------------------DFFAGLRSLRTL 354
            :..:.::|.|..|:.:....|:||.:  ||                       |.|....:|:||
Mosquito   274 QFPTLALRQLEHLRLVRLSMNEIASLEPDDSYTRFGALSFLDLSLNNFAELYGDIFGAFPALKTL 338

  Fly   355 SLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAF--------VELNN------------- 398
            ||:||.|..:....|.:|..|.:|||:.|||.::|.:.|        |:|:.
Mosquito   339 SLYNNFIEQVHRDAFVSLHELQSLDLSHNRIVYLDPDVFAANRRLHTVDLSRNHVHYVSGVFANL 403

  Fly   399 --LNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFD 461
              |.|:||.:|::..:..|.|.|.:.:..|.:..|.|..|:.:....|.:|:.|.|::|:|:...
Mosquito   404 PVLREVFLSENNLLELTDDCFANSTGVKVLYMEHNALQRLDGEALASLASLEQLFLSHNLLEKIP 468

  Fly   462 ARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKN 503
            .|.|||..:|..|.:|.|.|:.|..........|..::|:.|
Mosquito   469 VRFFEPTPELTSLALDGNALLELDERLFQRQGKLRELRLNGN 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	18/83 (22%)
		leucine-rich repeat	187..206	CDD:275380	7/18 (39%)
		LRR_RI	<201..386	CDD:238064	66/234 (28%)
		leucine-rich repeat	207..230	CDD:275380	7/23 (30%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		LRR_8	253..313	CDD:290566	25/60 (42%)
		leucine-rich repeat	255..278	CDD:275380	11/22 (50%)
		leucine-rich repeat	279..302	CDD:275380	8/23 (35%)
		LRR_8	303..361	CDD:290566	23/82 (28%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	8/47 (17%)
		LRR_8	349..407	CDD:290566	25/80 (31%)
		LRR_4	350..390	CDD:289563	17/39 (44%)
		leucine-rich repeat	351..374	CDD:275380	10/22 (45%)
		leucine-rich repeat	375..398	CDD:275380	11/30 (37%)
		LRR_8	398..>443	CDD:290566	12/59 (20%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		leucine-rich repeat	423..443	CDD:275380	4/19 (21%)
		leucine-rich repeat	471..494	CDD:275380	6/22 (27%)
		LRRCT	503..554	CDD:214507	1/1 (100%)
AgaP_AGAP000360	XP_310751.5	leucine-rich repeat	166..188	CDD:275380	7/21 (33%)
		LRR_8	188..247	CDD:290566	20/59 (34%)
		leucine-rich repeat	190..213	CDD:275380	6/22 (27%)
		leucine-rich repeat	214..236	CDD:275380	11/22 (50%)
		LRR_8	236..296	CDD:290566	18/59 (31%)
		leucine-rich repeat	237..261	CDD:275380	8/23 (35%)
		leucine-rich repeat	262..285	CDD:275380	8/22 (36%)
		LRR_RI	267..512	CDD:238064	64/244 (26%)
		leucine-rich repeat	286..310	CDD:275380	6/23 (26%)
		leucine-rich repeat	311..334	CDD:275380	2/22 (9%)
		LRR_8	314..369	CDD:290566	17/54 (31%)
		leucine-rich repeat	335..358	CDD:275380	10/22 (45%)
		LRR_8	358..416	CDD:290566	16/57 (28%)
		leucine-rich repeat	359..382	CDD:275380	9/22 (41%)
		leucine-rich repeat	383..405	CDD:275380	2/21 (10%)
		LRR_8	404..464	CDD:290566	17/59 (29%)
		leucine-rich repeat	406..429	CDD:275380	8/22 (36%)
		leucine-rich repeat	430..453	CDD:275380	5/22 (23%)
		LRR_8	453..512	CDD:290566	18/58 (31%)
		leucine-rich repeat	454..477	CDD:275380	9/22 (41%)
		leucine-rich repeat	478..501	CDD:275380	6/22 (27%)
		LRR_8	501..560	CDD:290566	3/10 (30%)
		leucine-rich repeat	502..525	CDD:275380	3/9 (33%)
		leucine-rich repeat	526..547	CDD:275380
		LRR_RI	548..791	CDD:238064
		leucine-rich repeat	613..636	CDD:275380
		LRR_8	615..671	CDD:290566
		leucine-rich repeat	637..660	CDD:275380
		LRR_8	660..743	CDD:290566
		leucine-rich repeat	661..684	CDD:275380
		leucine-rich repeat	685..708	CDD:275380
		leucine-rich repeat	709..732	CDD:275380
		leucine-rich repeat	733..756	CDD:275380
		LRR_RI	735..1027	CDD:238064
		leucine-rich repeat	757..780	CDD:275380
		leucine-rich repeat	781..803	CDD:275380
		leucine-rich repeat	804..827	CDD:275380
		LRR_8	827..886	CDD:290566
		leucine-rich repeat	828..851	CDD:275380
		leucine-rich repeat	852..875	CDD:275380
		leucine-rich repeat	876..899	CDD:275380
		LRR_8	877..934	CDD:290566
		leucine-rich repeat	900..923	CDD:275380
		LRR_RI	902..1176	CDD:238064
		LRR_8	922..982	CDD:290566
		leucine-rich repeat	924..947	CDD:275380
		leucine-rich repeat	948..968	CDD:275380
		leucine-rich repeat	972..997	CDD:275380
		LRR_8	997..1057	CDD:290566
		leucine-rich repeat	998..1025	CDD:275380
		leucine-rich repeat	1026..1070	CDD:275380
		LRR_8	1045..1105	CDD:290566
		leucine-rich repeat	1071..1094	CDD:275380
		LRR_8	1093..1152	CDD:290566
		leucine-rich repeat	1095..1117	CDD:275380
		leucine-rich repeat	1118..1141	CDD:275380
		LRR_8	1142..1197	CDD:290566
		leucine-rich repeat	1142..1163	CDD:275380
		leucine-rich repeat	1166..1187	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910