DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and LRG1

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_443204.1 Gene:LRG1 / 116844 HGNCID:29480 Length:347 Species:Homo sapiens


Alignment Length:258 Identity:79/258 - (30%)
Similarity:116/258 - (44%) Gaps:5/258 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly   289 IQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRT 353
            :.:.|.|||:....|:||.:|.|.:..||...:|.:.:|:.||...|.:..:....|....:|.|
Human    80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDT 144

  Fly   354 LSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFL 418
            |.|..|::..|..:..:.|..|..|||:.||:..:..........|..|.||:|.:.::|.||..
Human   145 LVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLR 209

  Fly   419 NVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMF 483
            ....|.||.|..|.|..|..|......:|:.|.||.|.|....|.||:.|.||:.|.:.:|.|..
Human   210 GPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLAS 274

  Fly   484 LPHG--ALHGLKN---LVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGG 541
            :|.|  |..|..|   .....:..|||.||.....|.||::....|::......|.||..:.|
Human   275 VPEGLWASLGQ
PNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKG 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566
leucine-rich repeat 187..206 CDD:275380
LRR_RI <201..386 CDD:238064 30/96 (31%)
leucine-rich repeat 207..230 CDD:275380
leucine-rich repeat 231..254 CDD:275380
LRR_8 253..313 CDD:290566 9/23 (39%)
leucine-rich repeat 255..278 CDD:275380
leucine-rich repeat 279..302 CDD:275380 4/12 (33%)
LRR_8 303..361 CDD:290566 18/57 (32%)
leucine-rich repeat 303..326 CDD:275380 8/22 (36%)
leucine-rich repeat 327..350 CDD:275380 5/22 (23%)
LRR_8 349..407 CDD:290566 17/57 (30%)
LRR_4 350..390 CDD:289563 13/39 (33%)
leucine-rich repeat 351..374 CDD:275380 7/22 (32%)
leucine-rich repeat 375..398 CDD:275380 6/22 (27%)
LRR_8 398..>443 CDD:290566 16/44 (36%)
leucine-rich repeat 399..422 CDD:275380 8/22 (36%)
leucine-rich repeat 423..443 CDD:275380 8/19 (42%)
leucine-rich repeat 471..494 CDD:275380 8/24 (33%)
LRRCT 503..554 CDD:214507 13/39 (33%)
LRG1NP_443204.1 LRR_8 79..128 CDD:290566 16/47 (34%)
LRR_RI <82..248 CDD:238064 51/165 (31%)
LRR 1 93..114 7/20 (35%)
leucine-rich repeat 94..117 CDD:275380 8/22 (36%)
LRR_8 116..176 CDD:290566 17/59 (29%)
LRR 2 117..138 5/20 (25%)
leucine-rich repeat 118..141 CDD:275380 5/22 (23%)
LRR 3 141..162 6/20 (30%)
leucine-rich repeat 142..165 CDD:275380 7/22 (32%)
LRR 4 165..186 6/20 (30%)
leucine-rich repeat 166..189 CDD:275380 6/22 (27%)
LRR_8 169..224 CDD:290566 18/54 (33%)
LRR 5 189..210 8/20 (40%)
leucine-rich repeat 190..213 CDD:275380 8/22 (36%)
LRR_8 213..272 CDD:290566 22/58 (38%)
LRR 6 213..234 8/20 (40%)
leucine-rich repeat 214..237 CDD:275380 8/22 (36%)
LRR 7 237..258 9/20 (45%)
leucine-rich repeat 238..261 CDD:275380 10/22 (45%)
LRR 8 261..282 7/20 (35%)
leucine-rich repeat 262..285 CDD:275380 7/22 (32%)
LRRCT 299..346 CDD:214507 13/39 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141288
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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