DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and LOC110439874

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_021332862.1	Gene:	LOC110439874 / 110439874	-ID:	-	Length:	804	Species:	Danio rerio

Alignment Length:	470	Identity:	125/470 - (26%)
Similarity:	209/470 - (44%)	Gaps:	43/470 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 FDLVKRVRQIESRLRSVEQPVWHLATGSQIEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPV--TQ 177
            ||  |.|..|...|:.....::.:.:...|    ...|....||..|......|:.:||.|  .:
Zfish    62 FD--KSVTTIPENLKDGADEIFFVNSKIDI----IPKGAFSKNPQIKKLEFLGTSTESVEVGAFE 120

  Fly   178 VIPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLE 242
            .:| ::..|::|...:::|....|:.|..|:.|.:..|.::.|...||.||..|..|.:..|::.
Zfish   121 GLP-DIATIEISSTNVTSLPVGVFKDLVNLQRLVLKSNKINILEKGLFDDLTQLQELFLHMNEIT 184

  Fly   243 DIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELD 307
            .|:..||..|.||.:|.|:||.:..:..|:|...:.|.:..:.:|.:...|..:......|.|:.
Zfish   185 AIEEGTFDNLENLRLLHLAKNNLNSVSTSLFSKLKSLRIFRLYENLLTAMPDGIFDSLSDLTEIA 249

  Fly   308 MSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNL 372
            :..|:||.|......:.:|:..|....|.:.:::.:.|.|..||::|:||||:::||...:|.
Zfish   250 LQGNQISSLQPNLFPHKSKIVKLFLDHNLLTELEQELFVGFISLKSLTLHNNQLTSLPNVLFG-- 312

  Fly   373 ANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLE 437
                                  |:..|.||.|..|:::.:|..:|..:..|.:|.|.||:.:.:.
Zfish   313 ----------------------EMPKLTELSLNHNNLTHLPPGVFSPLKKLKKLDLSSNHFSMIS 355

  Fly   438 ADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDK 502
            .|.|:||..|..|.|.||.:|:.....|:.|..|..||::.|||..||.........|..:.|:.
Zfish   356 GDFFEGLEKLADLNLQNNYIKSLKQEDFDKLPLLSILRLEHNKLQNLPADVFDSHPKLSKLYLNN 420

  Fly   503 NPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDL-CDGQWASMLSLSPR 566
            |||.|||..|....|:::...|: ..:.|:|..|..|....:......|| |      :.:|.|.
Zfish   421 NPWQCDCNLLPFFEWLKDNEDKV-KSKPPLCESPNHLLNQPIPSFEEKDLIC------LTTLPPT 478

  Fly   567 LPVRKHQISTPMNYT 581
            .|:.  ..:.||..|
Zfish   479 TPLL--TTTVPMTTT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	16/58 (28%)
		leucine-rich repeat	187..206	CDD:275380	4/18 (22%)
		LRR_RI	<201..386	CDD:238064	49/184 (27%)
		leucine-rich repeat	207..230	CDD:275380	8/22 (36%)
		leucine-rich repeat	231..254	CDD:275380	7/22 (32%)
		LRR_8	253..313	CDD:290566	14/59 (24%)
		leucine-rich repeat	255..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	3/22 (14%)
		LRR_8	303..361	CDD:290566	18/57 (32%)
		leucine-rich repeat	303..326	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	4/22 (18%)
		LRR_8	349..407	CDD:290566	15/57 (26%)
		LRR_4	350..390	CDD:289563	10/39 (26%)
		leucine-rich repeat	351..374	CDD:275380	9/22 (41%)
		leucine-rich repeat	375..398	CDD:275380	1/22 (5%)
		LRR_8	398..>443	CDD:290566	14/44 (32%)
		leucine-rich repeat	399..422	CDD:275380	7/22 (32%)
		leucine-rich repeat	423..443	CDD:275380	7/19 (37%)
		leucine-rich repeat	471..494	CDD:275380	8/22 (36%)
		LRRCT	503..554	CDD:214507	15/51 (29%)
LOC110439874	XP_021332862.1	NEL	<125..>331	CDD:330839	58/229 (25%)
		leucine-rich repeat	149..172	CDD:275380	8/22 (36%)
		leucine-rich repeat	173..196	CDD:275380	7/22 (32%)
		leucine-rich repeat	197..220	CDD:275380	7/22 (32%)
		leucine-rich repeat	221..244	CDD:275380	3/22 (14%)
		leucine-rich repeat	245..268	CDD:275380	6/22 (27%)
		leucine-rich repeat	269..292	CDD:275380	4/22 (18%)
		leucine-rich repeat	293..316	CDD:275380	10/46 (22%)
		LRR_8	315..399	CDD:316378	28/83 (34%)
		leucine-rich repeat	317..340	CDD:275380	7/22 (32%)
		leucine-rich repeat	341..364	CDD:275380	9/22 (41%)
		leucine-rich repeat	365..388	CDD:275380	8/22 (36%)
		leucine-rich repeat	389..412	CDD:275380	8/22 (36%)
		LRRCT	421..471	CDD:214507	15/50 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D595054at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010