Protein Alignment CG7509 and CHAD

DIOPT Version :10

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: XP_054170751.1
• Gene: CHAD / 1101
• HGNCID: 1909
• Length: 440
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 94/394 - (23%)
• Similarity: 154/394 - (39%)
• Gaps: 86/394 - (21%)

  Fly   154 CRCNPDTKSFTCWNTNLKSVP-VTQVIPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVL 217
            |.|:.|.:...|....|:.:| |::...:    ::|.||....|..::||.
Human   108 CHCHSDLQHVICDKVGLQKIPKVSEKTKL----LNLQRNNFPVLAANSFRA-------------- 154

  Fly   218 DFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVI 282
                      :.:|:.|.:|:.|:.::....|..|:.|..|.||.|:|.:|....|.....||.:
Human   155 ----------MPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYL 209

  Fly   283 NMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAG 347
            .:..|::...|..||...:.|..|.::.|||.||.:|:                        |.|
Human   210 YLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGA------------------------FQG 250

  Fly   348 LRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSI 412
            .:.||.|.|..|.:|||.....:::.||....:..|::|.....|..:|..:.||.|..|.:.||
Human   251 AKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSI 315

  Fly   413 PADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRID 477
            |.:.|.:         |...|.|              |.|:|..|:.|...||..::.|:.:.::
Human   316 PDNAFQS---------FGRYLET--------------LWLDNTNLEKFSDGAFLGVTTLKHVHLE 357

  Fly   478 SNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQP--MCRGPGDLG 540
            :|:|..||..  ....:|..:.|..|||.|.|:...|.||:..      ...:|  .|..|....
Human   358 NNRLNQLPSN--FPFDSLETLALTNNPWKCTCQLRGLRRWLEA------KASRPDATCASPAKFK 414

  Fly   541 GHEV 544
            |..:
Human   415 GQHI 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR	185..>437	CDD:443914	61/251 (24%)
		leucine-rich repeat	187..206	CDD:275380	6/18 (33%)
		leucine-rich repeat	207..230	CDD:275380	0/22 (0%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	2/22 (9%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..398	CDD:275380	5/22 (23%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		leucine-rich repeat	423..443	CDD:275380	3/19 (16%)
		leucine-rich repeat	471..494	CDD:275380	5/22 (23%)
		PCC	476..>561	CDD:188093	18/71 (25%)
CHAD	XP_054170751.1	LRRNT	104..130	CDD:396168	6/21 (29%)
		LRR	131..>382	CDD:443914	75/327 (23%)
		leucine-rich repeat	134..157	CDD:275380	6/50 (12%)
		leucine-rich repeat	158..181	CDD:275380	6/22 (27%)
		leucine-rich repeat	182..205	CDD:275380	8/22 (36%)
		leucine-rich repeat	206..229	CDD:275380	6/22 (27%)
		leucine-rich repeat	230..253	CDD:275380	10/46 (22%)
		leucine-rich repeat	254..277	CDD:275380	8/22 (36%)
		leucine-rich repeat	278..301	CDD:275380	5/22 (23%)
		leucine-rich repeat	302..325	CDD:275380	9/31 (29%)
		leucine-rich repeat	327..350	CDD:275380	9/36 (25%)
		leucine-rich repeat	351..373	CDD:275380	5/23 (22%)
		LRRCT	381..428	CDD:214507	12/44 (27%)