DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7509 and LOC101882092

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_005164829.1	Gene:	LOC101882092 / 101882092	-ID:	-	Length:	678	Species:	Danio rerio

Alignment Length:	466	Identity:	108/466 - (23%)
Similarity:	185/466 - (39%)	Gaps:	112/466 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 SAANDKKPPKSKANGHNDGDVNGG-----------EINAMSHLANFDLVKRVRQI--ESRLRSVE 132
            |...||  .|||...|.|.....|           :...:|..|     |:|:::  |.:|:.
Zfish   238 STFTDK--AKSKVAKHKDNKTLKGKKKKAVKGKPRKTTKVSKKA-----KKVKKLNHEQKLKP-- 293

  Fly   133 QPVWHLATGSQ---IEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPMNMVNIDLSRNILS 194
                  .|.|.   .|.|:|.|   .|:...:...|.:.:|..:|..  ||.|...|.|..|.:.
Zfish   294 ------TTPSHFPYFEDNYCPS---ECSCYGRVVQCSDKHLVKIPYG--IPYNSRYILLMNNKID 347

  Fly   195 TLH-------------------------KDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVL 234
            ::.                         |..|.|:..||.|.:..|:|..:|.||...|:.   |
Zfish   348 SIQLNLLSQYDSMEFLVLRNNRLTDSAVKKAFEGIQRLKRLYVERNLLRSIPTDLPATLEE---L 409

  Fly   235 RIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFP---PNL 296
            |:..||:..:.:..|.:..:|.||.||.|.:..:|..:......|..:.:..||:.:.|   |..
Zfish   410 RLDWNQISAMSNAAFERCPSLQILSLSNNTLLTIPPGVLLPLGSLRTLTLSYNQLASVPMQLPLS 474

  Fly   297 LRDQLM------------------LEELDMSRNKISELSSGSIRYL--TKLKTLDFGWNQIAKID 341
            ||:..:                  |:.||:|.|::::...|....|  |.|::|:...|.:.::.
Zfish   475 LRELYLRGNRIQRLQGDMFWGESELQILDLSLNRLTDKGLGKAALLNATGLESLNLEGNLLKRVP 539

  Fly   342 DDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQ 406
            ...   ..:::||:|..|.|.|::...|.::..|..|.|..|:|:.:...||..|..|::|.:..
Zfish   540 RHL---PHTIKTLNLEGNFILSITKDAFVSMPQLEHLGLARNKIAKVALGAFRVLPLLHQLDMSY 601

  Fly   407 NSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDF-QGLNNLKILLLNNNILKNFDARAFEPLSQ 470
            |::..:|..|.|   .|...|...||:.::..|.| .|.:|:                  .|||:
Zfish   602 NALEQVPRQLPL---WLHSATFMHNNIRSIPRDAFCWGRDNV------------------SPLSR 645

  Fly   471 LEKLRIDSNKL 481
            |.|::::.|.:
Zfish   646 LVKVQLEYNMI 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	19/83 (23%)
		leucine-rich repeat	187..206	CDD:275380	5/43 (12%)
		LRR_RI	<201..386	CDD:238064	52/207 (25%)
		leucine-rich repeat	207..230	CDD:275380	9/22 (41%)
		leucine-rich repeat	231..254	CDD:275380	5/22 (23%)
		LRR_8	253..313	CDD:290566	19/80 (24%)
		leucine-rich repeat	255..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	7/25 (28%)
		LRR_8	303..361	CDD:290566	15/59 (25%)
		leucine-rich repeat	303..326	CDD:275380	7/24 (29%)
		leucine-rich repeat	327..350	CDD:275380	3/22 (14%)
		LRR_8	349..407	CDD:290566	17/57 (30%)
		LRR_4	350..390	CDD:289563	12/39 (31%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	8/22 (36%)
		LRR_8	398..>443	CDD:290566	12/45 (27%)
		leucine-rich repeat	399..422	CDD:275380	6/22 (27%)
		leucine-rich repeat	423..443	CDD:275380	6/20 (30%)
		leucine-rich repeat	471..494	CDD:275380	3/11 (27%)
		LRRCT	503..554	CDD:214507
LOC101882092	XP_005164829.1	LRRNT	307..335	CDD:214470	8/32 (25%)
		leucine-rich repeat	316..334	CDD:275380	4/19 (21%)
		leucine-rich repeat	337..359	CDD:275380	3/21 (14%)
		LRR_RI	360..596	CDD:238064	58/241 (24%)
		leucine-rich repeat	360..384	CDD:275380	3/23 (13%)
		leucine-rich repeat	385..404	CDD:275380	8/18 (44%)
		LRR_8	405..464	CDD:290566	15/61 (25%)
		leucine-rich repeat	406..429	CDD:275380	6/25 (24%)
		leucine-rich repeat	430..453	CDD:275380	7/22 (32%)
		leucine-rich repeat	454..474	CDD:275380	5/19 (26%)
		LRR_8	474..535	CDD:290566	13/60 (22%)
		leucine-rich repeat	475..498	CDD:275380	2/22 (9%)
		leucine-rich repeat	499..524	CDD:275380	7/24 (29%)
		leucine-rich repeat	525..544	CDD:275380	3/21 (14%)
		leucine-rich repeat	546..569	CDD:275380	7/22 (32%)
		LRR_8	547..604	CDD:290566	18/56 (32%)
		leucine-rich repeat	570..593	CDD:275380	8/22 (36%)
		leucine-rich repeat	618..645	CDD:275380	9/44 (20%)
		leucine-rich repeat	646..671	CDD:275380	3/11 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910