DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7509 and podn

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_003201285.2	Gene:	podn / 100536479	ZFINID:	ZDB-GENE-100922-117	Length:	593	Species:	Danio rerio

Alignment Length:	538	Identity:	122/538 - (22%)
Similarity:	203/538 - (37%)	Gaps:	162/538 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 PPKSKANGHNDGDVNGGEINAMSHLANFDLVKRVRQIESRLRSV-EQPVWHLATGSQIEWNH--- 148
            |.|...:|....|.||..::....    ||.::.||:..:...: |..:.||:...|:|..:
Zfish    51 PEKCSCSGEGAVDCNGVSLSEFPQ----DLSEQTRQLSLQNNQISEVTLEHLSRLQQLETLNLQN 111

  Fly   149 ---CTSGVCRCNPDTKSFTCW---------NTNLKSVPVTQVIPMNMVNIDLSRNILSTLHKDTF 201
               .|.|:     :.:.|...         |..|.:.|  :.:|.::|:.|.:.|.|:.:..:||
Zfish   112 NRLTTQGL-----EDEGFDILERLSYLYLANNKLTAAP--RHLPPSLVSADFAANQLTKIFPNTF 169

  Fly   202 ------------------RGL-----------------------------TVLKELDISHNVLDF 219
                              .||                             |.|..|.:.:|.|:.
Zfish   170 GQKPALKSVYLHNNKLTDAGLPESMFNGSDSLEILIMSSNFLRYVPKYLPTALYRLHLKNNKLEK 234

  Fly   220 LPFDLFQDLDSLLVLRIQNNQL--EDIDHRTFWKLRNLNILDLSKNEIGMLP------------- 269
            :|...|.:|..|..|.:|||.|  :.:|:.||..|.:|..||||.|.:..:|
Zfish   235 IPSGAFDNLFHLRELYLQNNFLSNDGMDNETFSHLNSLEYLDLSNNNLSTVPLGLPRNVILLHLE 299

  Fly   270 ----ESI------------------------------FYHAQRLTVINMCDNQIQNFPPNLLRDQ 300
                :||                              |...:||..::|.:|.::..|..|.|
Zfish   300 KNSIQSIAVNALSPIRNLEYLLLHNNRLRSRSIHPAAFQGLKRLHTVHMYNNLLERVPRGLPR-- 362

  Fly   301 LMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQI--AKIDDDFFAGLRSLRTLSLHNNRISS 363
             ..:.|.:..|.|||:....:..|..|..|:..:|::  ||:..:.|..||.|.||.|..|::.:
Zfish   363 -RAKTLMLLHNLISEIGRNDLITLYTLTELNLSYNRLTSAKLHREAFRKLRILETLDLSGNKLQA 426

  Fly   364 L----------------------SGTIFNNLANLVTLDLTTN--RISHIDGNAFVELNNLNELFL 404
            |                      .|.:. .:.:|..|.||.|  ::|.|...|::|:|.|..|.|
Zfish   427 LPLGLPKSLQILKVKDNQMTEIPEGALL-GMTSLRELYLTNNQLKLSSIYQGAWLEMNALKTLDL 490

  Fly   405 GQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLS 469
            ..|.:|.||.||   ..:|..|.|.:|.:.::....|....|:|.:.|..|.| :.::.:.|..:
Zfish   491 SGNMLSHIPPDL---PESLEFLHLQNNRINSISETAFLNTPNIKGIFLRFNRL-SVNSVSEETFA 551

  Fly   470 QLEKLRIDSNKLMFLPHG 487
            .|.|||:     :.:.||
Zfish   552 HLSKLRV-----LDIGHG 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	21/105 (20%)
		leucine-rich repeat	187..206	CDD:275380	7/65 (11%)
		LRR_RI	<201..386	CDD:238064	64/306 (21%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		leucine-rich repeat	231..254	CDD:275380	10/24 (42%)
		LRR_8	253..313	CDD:290566	19/106 (18%)
		leucine-rich repeat	255..278	CDD:275380	10/69 (14%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		LRR_8	303..361	CDD:290566	19/59 (32%)
		leucine-rich repeat	303..326	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	7/24 (29%)
		LRR_8	349..407	CDD:290566	21/81 (26%)
		LRR_4	350..390	CDD:289563	14/63 (22%)
		leucine-rich repeat	351..374	CDD:275380	7/44 (16%)
		leucine-rich repeat	375..398	CDD:275380	9/24 (38%)
		LRR_8	398..>443	CDD:290566	14/44 (32%)
		leucine-rich repeat	399..422	CDD:275380	9/22 (41%)
		leucine-rich repeat	423..443	CDD:275380	5/19 (26%)
		leucine-rich repeat	471..494	CDD:275380	6/17 (35%)
		LRRCT	503..554	CDD:214507
podn	XP_003201285.2	LRRNT	50..80	CDD:214470	8/32 (25%)
		leucine-rich repeat	80..103	CDD:275380	5/22 (23%)
		LRR_RI	<81..282	CDD:238064	46/207 (22%)
		LRR_8	83..140	CDD:290566	9/61 (15%)
		leucine-rich repeat	104..129	CDD:275380	4/29 (14%)
		leucine-rich repeat	130..174	CDD:275380	10/45 (22%)
		LRR_8	173..254	CDD:290566	13/80 (16%)
		leucine-rich repeat	175..200	CDD:275380	2/24 (8%)
		leucine-rich repeat	201..221	CDD:275380	0/19 (0%)
		LRR_RI	219..496	CDD:238064	70/280 (25%)
		LRR_8	222..282	CDD:290566	23/59 (39%)
		leucine-rich repeat	222..245	CDD:275380	7/22 (32%)
		leucine-rich repeat	246..271	CDD:275380	10/24 (42%)
		leucine-rich repeat	272..292	CDD:275380	7/19 (37%)
		leucine-rich repeat	293..316	CDD:275380	2/22 (9%)
		LRR_8	315..398	CDD:290566	17/85 (20%)
		leucine-rich repeat	317..342	CDD:275380	1/24 (4%)
		leucine-rich repeat	343..387	CDD:275380	12/46 (26%)
		LRR_8	387..469	CDD:290566	20/82 (24%)
		leucine-rich repeat	388..413	CDD:275380	7/24 (29%)
		leucine-rich repeat	414..434	CDD:275380	6/19 (32%)
		leucine-rich repeat	435..458	CDD:275380	1/23 (4%)
		LRR_8	457..516	CDD:290566	23/61 (38%)
		leucine-rich repeat	485..505	CDD:275380	9/22 (41%)
		LRR_8	505..566	CDD:290566	17/66 (26%)
		leucine-rich repeat	506..524	CDD:275380	4/17 (24%)
		leucine-rich repeat	530..555	CDD:275380	6/25 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910