Protein Alignment CG7509 and igfals

DIOPT Version :9

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: XP_002940278.2
• Gene: igfals / 100489984
• XenbaseID: XB-GENE-1008441
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 161/654 - (24%)
• Similarity: 255/654 - (38%)
• Gaps: 163/654 - (24%)

  Fly     5 VWQ-LVSLVLLMDPAEVITGPSQAKEPPIQSLDEFRQRYLLPLISSDTRNCSLNACESLGIV--S 66
            ||. ||...|..:|    ..|..|..||             |.:      ||.:..|...:.  |
 Frog    14 VWNILVCGSLEAEP----RSPEPAPCPP-------------PCV------CSYDYSEEYSVFCSS 55

  Fly    67 QLLMLINSMPNGTQSAANDKKPPKSKA---NGHNDGDVNGGEINAMSHLANFDLVKRVRQIESRL 128
            :.|..:...|           ||.:::   :|:|...|..|....:|||...:|.      .|::
 Frog    56 RNLTRVPEPP-----------PPAARSLWLDGNNLTTVQAGAFRNLSHLDFLNLQ------SSQV 103

  Fly   129 RSVEQPVWH---LATGSQIEWNHCTSGVCRCNPDTKSFTCWNTNLKSV-PVTQVIPMNMVNIDLS 189
            .|:||...|   ......:|.|                     .:||: |.|.....|:|::.|:
 Frog   104 ASLEQQALHGLKALAHLHLERN---------------------MIKSLAPSTFTHTQNLVSLTLN 147

  Fly   190 RNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSL--LVLR----------------- 235
            .|.|:.:....|.||:.|..|::..|:|..||..:|.||.:|  |||.
 Frog   148 NNFLTKIEDGLFSGLSNLWYLNLGWNLLVVLPDMVFHDLLNLRELVLAGNRLVYLQPSLFLSLGE 212

  Fly   236 -----------------------------IQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPES 271
                                         :.:|.:..:..|.|..::||..||||.|.:..|.|.
 Frog   213 LKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSHNRLTALYED 277

  Fly   272 IFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQ 336
            .|:....|.|:.:.:|.:.:..|.:.:|...|.||::.:|||..|...:...|.:|:.|....|.
 Frog   278 TFFGLPSLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQNKIKILLERTFEGLAQLELLSLNHNN 342

  Fly   337 IAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNE 401
            :.:|....|.||.::..::|..|.:.||:...|..|..|.:|.:.::.:|||....|..|:::..
 Frog   343 VQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCFKGLGKLHSLHMESSCLSHIKPQMFAGLSSIRR 407

  Fly   402 LFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFE 466
            |||..|.:.:|....|.::..|..|.|.||.||.|....|.||.||..|||::|.:.......|.
 Frog   408 LFLQNNEIVAIEDHSFTDLHGLLELDLRSNKLTHLTTRSFTGLKNLSYLLLSSNQILTISPEVFS 472

  Fly   467 PLSQLEKLRIDSNKL------MFLPHGALH--GLKN----LVAVK------------LDKNPWHC 507
            |:.||:.|.:..|:|      :|||..:|.  .|||    .::|.            |:.|.|.|
 Frog   473 PVQQLQWLDLSDNQLKALTEDIFLPLSSLRYLSLKNNCLKTISVNFLIPPPTMQQLWLNGNQWDC 537

  Fly   508 DCR-------ALYLARWIREFVLKLWDGQ---QPM-----CRGPGDLGGHEVGLLRYDDLCDGQW 557
            .|.       ||..:..:...|..:.:|.   .|:     |..|.:..|.::     .||.:|.:
 Frog   538 GCALKGLRDLALRNSTIVPHLVQSISEGDDTASPVYNNITCASPPEAMGQDI-----RDLSEGHF 597

  Fly   558 ASML 561
            |..|
 Frog   598 AHCL 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	22/106 (21%)
		leucine-rich repeat	187..206	CDD:275380	6/18 (33%)
		LRR_RI	<201..386	CDD:238064	57/232 (25%)
		leucine-rich repeat	207..230	CDD:275380	9/22 (41%)
		leucine-rich repeat	231..254	CDD:275380	7/70 (10%)
		LRR_8	253..313	CDD:290566	19/59 (32%)
		leucine-rich repeat	255..278	CDD:275380	9/22 (41%)
		leucine-rich repeat	279..302	CDD:275380	5/22 (23%)
		LRR_8	303..361	CDD:290566	17/57 (30%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	7/22 (32%)
		LRR_8	349..407	CDD:290566	16/57 (28%)
		LRR_4	350..390	CDD:289563	11/39 (28%)
		leucine-rich repeat	351..374	CDD:275380	6/22 (27%)
		leucine-rich repeat	375..398	CDD:275380	7/22 (32%)
		LRR_8	398..>443	CDD:290566	15/44 (34%)
		leucine-rich repeat	399..422	CDD:275380	6/22 (27%)
		leucine-rich repeat	423..443	CDD:275380	9/19 (47%)
		leucine-rich repeat	471..494	CDD:275380	9/30 (30%)
		LRRCT	503..554	CDD:214507	14/65 (22%)
igfals	XP_002940278.2	leucine-rich repeat	69..92	CDD:275380	4/22 (18%)
		PLN00113	71..>534	CDD:215061	125/489 (26%)
		leucine-rich repeat	93..116	CDD:275380	7/28 (25%)
		leucine-rich repeat	117..140	CDD:275380	6/43 (14%)
		leucine-rich repeat	141..164	CDD:275380	7/22 (32%)
		leucine-rich repeat	165..188	CDD:275380	9/22 (41%)
		leucine-rich repeat	189..212	CDD:275380	4/22 (18%)
		leucine-rich repeat	213..236	CDD:275380	0/22 (0%)
		leucine-rich repeat	237..260	CDD:275380	3/22 (14%)
		leucine-rich repeat	261..284	CDD:275380	9/22 (41%)
		leucine-rich repeat	285..308	CDD:275380	5/22 (23%)
		leucine-rich repeat	309..332	CDD:275380	8/22 (36%)
		leucine-rich repeat	333..354	CDD:275380	5/20 (25%)
		leucine-rich repeat	357..380	CDD:275380	6/22 (27%)
		leucine-rich repeat	381..404	CDD:275380	7/22 (32%)
		leucine-rich repeat	405..428	CDD:275380	6/22 (27%)
		leucine-rich repeat	429..450	CDD:275380	9/20 (45%)
		leucine-rich repeat	453..472	CDD:275380	5/18 (28%)
		leucine-rich repeat	477..500	CDD:275380	7/22 (32%)
		leucine-rich repeat	525..537	CDD:275378	3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910