DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and LOC100485206

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_002931661.1	Gene:	LOC100485206 / 100485206	-ID:	-	Length:	790	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	95/336 - (28%)
Similarity:	147/336 - (43%)	Gaps:	65/336 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 HLANFD-LVKRVRQIESRLRSVEQ-PVWHLATGSQIEWNHCTSGVCRCNPDT------KSFTCWN 167
            |.|.|. |::.::.:..:..:::| |:|.... |.:|..|.   :|..:||.      :||...|
Frog   468 HTAAFAFLMEHLQTLTVKFDNIQQIPLWIYGL-SCLEELHL---ICSQSPDVAKNITFESFKNLN 528

  Fly   168 TNLKSVPV-TQV--IPMNMVNIDLSRNILSTLHKDTFR-----------GLTVLKELDISHNVLD 218
             |||.:.: :|:  ||.|:.:|.|.....| :|.:..:           .||||:.:..:   |.
Frog   529 -NLKHLFIKSQLSGIPQNVTDISLQLQRFS-IHNEGIKLVIPNSLKKMVNLTVLELIQCN---LG 588

  Fly   219 FLPFDLFQDLDSLLVLRIQNNQLEDIDH-RTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLT-- 280
            .:|..:| .|.:|..|.::.|.|..|.. .:|..|.||.||.|..|:|..:|:    |..:||
Frog   589 HVPNSIF-SLRALKELNLEGNNLRSIQELASFQHLHNLTILKLWHNKIAKIPD----HINKLTNL 648

  Fly   281 -VINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDF 344
             .:|:..|.|:..|.:|.... .|..||:|.|.|. :....|..|..||......|::..|.::.
Frog   649 EQLNLSHNNIREIPHSLFLCS-KLRYLDLSYNDIC-IIQPYIWMLQSLKYFSIKCNKVEIIPNEL 711

  Fly   345 FAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHID--GNAFVELN---------N 398
            |. .|.|.||:|..|::..||    .|:.||..|       ||:|  ||....|.         |
Frog   712 FL-CRRLETLNLGKNKLHCLS----PNIGNLEFL-------SHLDIKGNCIRALPPELGCCKSLN 764

  Fly   399 LNELFLGQNSM 409
            .|||.:..|.|
Frog   765 KNELIIEDNMM 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	16/69 (23%)
		leucine-rich repeat	187..206	CDD:275380	4/29 (14%)
		LRR_RI	<201..386	CDD:238064	56/199 (28%)
		leucine-rich repeat	207..230	CDD:275380	5/22 (23%)
		leucine-rich repeat	231..254	CDD:275380	7/23 (30%)
		LRR_8	253..313	CDD:290566	21/62 (34%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	7/25 (28%)
		LRR_8	303..361	CDD:290566	19/57 (33%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	5/22 (23%)
		LRR_8	349..407	CDD:290566	22/68 (32%)
		LRR_4	350..390	CDD:289563	14/41 (34%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..398	CDD:275380	8/33 (24%)
		LRR_8	398..>443	CDD:290566	6/12 (50%)
		leucine-rich repeat	399..422	CDD:275380	5/11 (45%)
		leucine-rich repeat	423..443	CDD:275380
		leucine-rich repeat	471..494	CDD:275380
		LRRCT	503..554	CDD:214507
LOC100485206	XP_002931661.1	Pannexin_like	1..324	CDD:372171
		leucine-rich repeat	411..431	CDD:275380
		leucine-rich repeat	432..454	CDD:275380
		leucine-rich repeat	479..501	CDD:275380	3/22 (14%)
		leucine-rich repeat	502..529	CDD:275380	8/30 (27%)
		LRR	520..784	CDD:227223	82/280 (29%)
		leucine-rich repeat	530..552	CDD:275380	7/21 (33%)
		leucine-rich repeat	553..576	CDD:275380	2/23 (9%)
		leucine-rich repeat	577..599	CDD:275380	8/25 (32%)
		leucine-rich repeat	600..624	CDD:275380	7/23 (30%)
		leucine-rich repeat	625..647	CDD:275380	9/25 (36%)
		leucine-rich repeat	648..670	CDD:275380	5/22 (23%)
		leucine-rich repeat	694..716	CDD:275380	5/22 (23%)
		leucine-rich repeat	717..739	CDD:275380	10/25 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910