DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7509 and slitrk3

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_002933279.1	Gene:	slitrk3 / 100127669	XenbaseID:	XB-GENE-964617	Length:	885	Species:	Xenopus tropicalis

Alignment Length:	530	Identity:	124/530 - (23%)
Similarity:	196/530 - (36%)	Gaps:	148/530 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 NMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDH 246
            |.|:|::..|.|..:....|.||.|||.|.:..|.||....|.|..|:||..|:...|.::.|:.
Frog   102 NAVSINMGNNALQDIQAGAFNGLKVLKRLYLHENKLDSFKNDTFLGLESLEYLQADYNVIKRIES 166

  Fly   247 RTFWKLRNLNILDLSKNEIGMLPESIF---------YHAQRLTVI---NMCD------------- 286
            ..|..|..|.:|.|:.|.|.:||.::|         ....||.::   .|.|
Frog   167 GAFRYLNKLRVLILNDNHIPLLPTNLFKSVSLTHLDLRGNRLKILFYKGMLDHIGRSLMEIQLAE 231

  Fly   287 -------------NQIQNFPPNLLRDQLMLEE---------LDMSRNKI---------------- 313
                         |.::..|..:|...:..|.         .|:.|:|:
Frog   232 NPWNCTCEILQLKNWLERIPYTVLVGDITCESPFHFHGKDLRDIKRSKLCPSLTESEAEISWGIP 296

  Fly   314 --------------------SELSSGSIRYLTKLKT------------------LDFGWNQ--IA 338
                                |.:::.|:.|.:..|.                  |..|.||  ||
Frog   297 QIPSSKENAWPTKPSSMLSSSHVTASSVEYKSSNKQPTTTKQPRAPKPPPTPRGLYPGPNQPPIA 361

  Fly   339 --------------------KIDDDFFAGLR-------------------SLRTLSLHNNRISSL 364
                                .|:|   .||.                   :.:.|.|:.|.|..:
Frog   362 GYQTRPPIPIICPTGCSCSLHIND---LGLTVNCKERGFHNISELLPRPLNAKKLYLNGNLIQKI 423

  Fly   365 SGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLF 429
            ..:.|.|.::|..|.|..||||::...|||.|.||..|:|..|.:..:...:|..:.:|..|...
Frog   424 YRSDFWNFSSLDLLHLGNNRISYVQEGAFVNLPNLKNLYLNGNDIERLTPGMFRGLQSLHYLYFE 488

  Fly   430 SNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLP-HGALHGLK 493
            .|.:..::...|..:.|||:|.||:|:|:......|...| |.:|.:.:|..::|| .|.|..|.
Frog   489 YNTIREIQPAAFSLMPNLKLLFLNDNLLRTLPTDTFAGTS-LSRLNLRNNHFLYLPVTGVLEHLN 552

  Fly   494 NLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDLCDGQWA 558
            .:|.:.|::|||.|.|..:.|.:||......:..| :.:|..|.:|...::..:....||.....
Frog   553 AIVQIDLNQNPWDCTCDIVPLKQWIETISSVIVVG-EVLCASPENLTNKDLKSIDMKVLCPELLD 616

  Fly   559 SMLSLSPRLP 568
            |..:.||.||
Frog   617 SEAAASPALP 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	22/58 (38%)
		leucine-rich repeat	187..206	CDD:275380	5/18 (28%)
		LRR_RI	<201..386	CDD:238064	64/326 (20%)
		leucine-rich repeat	207..230	CDD:275380	9/22 (41%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		LRR_8	253..313	CDD:290566	18/106 (17%)
		leucine-rich repeat	255..278	CDD:275380	8/31 (26%)
		leucine-rich repeat	279..302	CDD:275380	6/51 (12%)
		LRR_8	303..361	CDD:290566	21/161 (13%)
		leucine-rich repeat	303..326	CDD:275380	7/67 (10%)
		leucine-rich repeat	327..350	CDD:275380	11/81 (14%)
		LRR_8	349..407	CDD:290566	21/76 (28%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	6/22 (27%)
		leucine-rich repeat	375..398	CDD:275380	11/22 (50%)
		LRR_8	398..>443	CDD:290566	10/44 (23%)
		leucine-rich repeat	399..422	CDD:275380	5/22 (23%)
		leucine-rich repeat	423..443	CDD:275380	4/19 (21%)
		leucine-rich repeat	471..494	CDD:275380	8/23 (35%)
		LRRCT	503..554	CDD:214507	13/50 (26%)
slitrk3	XP_002933279.1	LRR_8	81..137	CDD:338972	13/34 (38%)
		leucine-rich repeat	81..102	CDD:275380	124/530 (23%)
		leucine-rich repeat	103..126	CDD:275380	7/22 (32%)
		LRR_8	127..185	CDD:338972	20/57 (35%)
		leucine-rich repeat	127..150	CDD:275380	9/22 (41%)
		leucine-rich repeat	151..174	CDD:275380	6/22 (27%)
		leucine-rich repeat	175..197	CDD:275380	8/21 (38%)
		leucine-rich repeat	198..283	CDD:275380	11/84 (13%)
		leucine-rich repeat	224..236	CDD:275378	0/11 (0%)
		LRRCT	232..>270	CDD:214507	4/37 (11%)
		LRR	<388..>562	CDD:227223	48/174 (28%)
		leucine-rich repeat	389..409	CDD:275380	0/19 (0%)
		leucine-rich repeat	410..433	CDD:275380	6/22 (27%)
		leucine-rich repeat	434..457	CDD:275380	11/22 (50%)
		LRR_8	457..516	CDD:338972	17/58 (29%)
		leucine-rich repeat	458..481	CDD:275380	5/22 (23%)
		leucine-rich repeat	482..505	CDD:275380	4/22 (18%)
		leucine-rich repeat	506..528	CDD:275380	8/21 (38%)
		leucine-rich repeat	529..553	CDD:275380	8/23 (35%)
		LRRCT	562..>597	CDD:214507	11/35 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910