| Sequence 1: | NP_001261425.1 | Gene: | RhoGEF64C / 38578 | FlyBaseID: | FBgn0035574 | Length: | 1984 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004454.2 | Gene: | FGD1 / 2245 | HGNCID: | 3663 | Length: | 961 | Species: | Homo sapiens |
| Alignment Length: | 626 | Identity: | 128/626 - (20%) |
|---|---|---|---|
| Similarity: | 218/626 - (34%) | Gaps: | 177/626 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1407 PIYEEIHEVPPPL-PLSAPPLNDAELEKKAARSI---FEGASKYDILSYLVDAKERGLAREESFD 1467
Fly 1468 YGNN-------------------------PKIIEEEAADTLSDLDKRQAE-ERERDRDSGQSSMS 1506
Fly 1507 SLS------------PPPHNFICGG-----------------AGKSSGSDVERQDSGVGSETSKT 1542
Fly 1543 SRSKYQATPTVLHLCEDCDGAVEMQVGDNGILYAPLVCRKCGKKRVERK--EIITEIVETEEKYG 1605
Fly 1606 RDLQIILEEFCHPMLVAGLLTQ---------EQLSAIFLNTEDLLENNQTLAERMRDALDMSLEQ 1661
Fly 1662 GDDDLLTVNIGRIFLDFTQMLHAFESYCVRQAGASLLLANLEKEKEL-LRIFLKVSQMENAVLRR 1725
Fly 1726 MNLNSFLMVPVQRVTKYPLLLARLYKVTPSHLEGRELLKQAQEKIEL---HLNHINQEAKDVP-- 1785
Fly 1786 ---TKLWRRISSS----SPNRRASCEIDMINIKLRKMAIDVLEWNHDEVRFAMEGRLLYTQPTDS 1843
Fly 1844 NWKKARTI-KLTPVNALLVTNGKPSANYRAEKAMSEKLNFPKHTGIREASLLLVKEKCGRYTLIR 1907
Fly 1908 EPLYLDRCVVCSEADWDDYFEVQEISSKDTFIFKAEDGVRT 1948 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF64C | NP_001261425.1 | RhoGEF | 1593..1779 | CDD:279015 | 48/198 (24%) |
| FGD1 | NP_004454.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..353 | 41/197 (21%) | |
| SH3-binding. /evidence=ECO:0000255 | 171..187 | 7/15 (47%) | |||
| RhoGEF | 376..559 | CDD:238091 | 48/198 (24%) | ||
| PH1_FGD1 | 591..698 | CDD:275392 | 30/149 (20%) | ||
| PH | 591..688 | CDD:278594 | 27/138 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 702..726 | ||||
| FYVE_FGD1_2_4 | 725..789 | CDD:277280 | |||
| PH2_FGD1-4 | 815..920 | CDD:270056 | |||
| PH | 823..921 | CDD:278594 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 925..961 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||