Protein Alignment CG12493 and STAU1

DIOPT Version :10

• Sequence 1: NP_647927.3
• Gene: CG12493 / 38575
• FlyBaseID: FBgn0035571
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_001309861.1
• Gene: STAU1 / 6780
• HGNCID: 11370
• Length: 583
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 49/246 - (19%)
• Similarity: 84/246 - (34%)
• Gaps: 90/246 - (36%)

  Fly   128 VNSKKYDAEGSSENSAGNAACEKALR----EILTTKMKALLAEPENSSGGDEDNILEKMTSYAVY 188
            |..::::.:|.:..:|.:.|..||||    |.|..:::.      |....:|:| |.|.....|:
Human   133 VGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEV------NGRESEEEN-LNKSEISQVF 190

  Fly   189 KLAEK----WNSDAIDVAALYND-----VKNKKTSSSVGQL------------------------ 220
            ::|.|    .|.::..:..:..:     :||..|..|||:.
Human   191 EIALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 255

  Fly   221 -------------PKLWKNMHPCMVLMQMRPQTT--------------------------FKFLG 246
                         |::.|...|.     ::|||:                          :..|.
Human   256 KKLPPLPAVERVKPRIKKKTKPI-----VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLT 315

  Fly   247 SSG-ENRKVFSMGVSVDNCEFKADGPTKKDARRKVAALVCNKLFGTDYPQA 296
            ..| ..|:.|.|.|.|.|...:..|..||.|:|..|..:. ::.|...|||
Human   316 ERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML-EILGFKVPQA 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12493	NP_647927.3	DSRM_SF	95..155	CDD:444671	8/30 (27%)
		DSRM_SF	227..284	CDD:444671	18/83 (22%)
STAU1	NP_001309861.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..55
		DSRM_STAU1_rpt2	82..146	CDD:380710	2/12 (17%)
		DSRM_SF	183..255	CDD:444671	11/71 (15%)
		DSRM_STAU1_rpt4	282..367	CDD:380714	20/85 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	366..403		49/246 (20%)
		Staufen_C	454..563	CDD:465131