Protein Alignment CG12493 and Adar

DIOPT Version :10

• Sequence 1: NP_647927.3
• Gene: CG12493 / 38575
• FlyBaseID: FBgn0035571
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_001344887.1
• Gene: Adar / 56417
• MGIID: 1889575
• Length: 1217
• Species: Mus musculus
• Alignment Length: 280
• Identity: 58/280 - (20%)
• Similarity: 98/280 - (35%)
• Gaps: 65/280 - (23%)

  Fly    14 VSDQEDAGMSDDLKETAMDCNMPDGESSLVITDGD--SMSKIPD--DAAMATSDPKKKKKKVKKL 74
            |:.:.....:||:         ||..:|:....|:  ::.::|.  ...:....|      .|||
Mouse   439 VASENGQWATDDI---------PDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSP------YKKL 488

  Fly    75 KRSQKAKDRLVRPLPKAVTSKDALMVLKELKGVIIDNMQIKQ---DHEGKNVANIVVNSKKY-DA 135
            ...|     |..|:       ..|:...:......|...|:|   .||.:....:|:|.::: .|
Mouse   489 TECQ-----LKNPV-------SGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPA 541

  Fly   136 EGSSENSAGNAACEKALREILTTKMKALLAEPENSSGGDEDNILEKMTSYAVYKLAEKWNSDAID 200
            |..|:..|...|..||:..:|.........:||:.|....:...||...      |:..:|.|
Mouse   542 EAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEDLSHCPMEEDSEKPAE------AQAPSSSA-- 598

  Fly   201 VAALYNDVKNKKTSSSVGQLP--KLWKNMHPCMVLMQMRPQTTFKFLGSSG-ENRKVFSMGVSVD 262
                        ||...|:.|  .|.:.||      ::.....|:.|...| .:...|...|:|.
Mouse   599 ------------TSLFSGKSPVTTLLECMH------KLGNSCEFRLLSKEGPAHDPKFQYCVAVG 645

  Fly   263 NCEF-KADGPTKKDARRKVA 281
            ...| ....|:||.|::..|
Mouse   646 AQTFPPVSAPSKKVAKQMAA 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12493	NP_647927.3	DSRM_SF	95..155	CDD:444671	15/63 (24%)
		DSRM_SF	227..284	CDD:444671	14/57 (25%)
Adar	NP_001344887.1	z-alpha	176..242	CDD:280459
		z-alpha	287..351	CDD:295419
		DSRM_DRADA_rpt1	494..564	CDD:380742	17/76 (22%)
		DSRM_SF	605..675	CDD:444671	16/67 (24%)
		DSRM_DRADA_rpt3	713..783	CDD:380744
		ADEAMc	827..1210	CDD:214718