Protein Alignment CG12493 and ZFR2

DIOPT Version :10

• Sequence 1: NP_647927.3
• Gene: CG12493 / 38575
• FlyBaseID: FBgn0035571
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: XP_011526133.1
• Gene: ZFR2 / 23217
• HGNCID: 29189
• Length: 940
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 48/230 - (20%)
• Similarity: 85/230 - (36%)
• Gaps: 70/230 - (30%)

  Fly    77 SQKAKDRLVRPLPKAVTSKDALMVLKELKGVIIDNMQIKQDHEGKNVANIVVNSKKYDAEGSSEN 141
            |:|....|:|.:        |..:.::|:.|..|..::..|.|    ||||::|
Human   681 SEKPTHSLLRRI--------AQQLPRQLQMVTEDEYEVSSDPE----ANIVISS----------- 722

  Fly   142 SAGNAACEKALREILTTKMKALLAEPENSSGGDEDNILEKMTSYAVYKLAEKWNSDAIDVAALYN 206
                  ||:...::..:....|:.|..::   |.:.:             |:..:||.||
Human   723 ------CEEPRMQVTISVTSPLMREDPST---DPEGV-------------EEPQADAGDV----- 760

  Fly   207 DVKNKKTSSSVGQLPKL-W-----KNMHPCMVLMQM-----RPQTTFKFLGSSGENRKVFSMGVS 260
             :..||...|:..|... |     ..:.||::::::     |...|:..|       ..::|.:.
Human   761 -LSPKKCLESLAALRHARWFQARASGLQPCVIVIRVLRDLCRRVPTWGAL-------PAWAMELL 817

  Fly   261 VDNCEFKADGPT-KKDARRKVAALVCNKLFGTDYP 294
            |:.....|.||. ..||.|:|...|......||.|
Human   818 VEKAVSSAAGPLGPGDAVRRVLECVATGTLLTDGP 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12493	NP_647927.3	DSRM_SF	95..155	CDD:444671	13/59 (22%)
		DSRM_SF	227..284	CDD:444671	14/62 (23%)
ZFR2	XP_011526133.1	PHA02732	<6..211	CDD:165099
		ZnF_U1	271..300	CDD:197732
		C2H2 Zn finger	273..295	CDD:275371
		ZnF_U1	318..350	CDD:197732
		C2H2 Zn finger	321..343	CDD:275371
		PRK12323	<356..>457	CDD:481241
		ZnF_U1	467..498	CDD:197732
		C2H2 Zn finger	470..492	CDD:275371
		ARGLU	<516..549	CDD:405931
		DZF	652..905	CDD:128842	48/230 (21%)