Protein Alignment CG12493 and ADARB1

DIOPT Version :10

• Sequence 1: NP_647927.3
• Gene: CG12493 / 38575
• FlyBaseID: FBgn0035571
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: XP_047296616.1
• Gene: ADARB1 / 104
• HGNCID: 226
• Length: 772
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 78/336 - (23%)
• Similarity: 120/336 - (35%)
• Gaps: 85/336 - (25%)

  Fly    12 VNVSDQED-AGMSDDLKE-------TAMDCNMP-DGESSLVITDGDSMSKIPDDAAMATSDPKKK 67
            :::.|:|: :..|.|:||       :..|.:.| .||.|.:...|.             ..|.:|
Human    32 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGG-------------GGPGRK 83

  Fly    68 KKKVKKLKRSQKAKDRLVRPLPKAVTSKDALMVLKELKGVIIDNM--QIKQDHEGKNVANIVVNS 130
            :...:......|.:.:..|..|..|..|:|||.|.|:|..:...:  |....|....|.::.||.
Human    84 RPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNG 148

  Fly   131 KKYDAEGSSENSAGNAACEKALREIL--TTKMKALLAEPENSSGGDEDNILEKMTSYAVYKLAEK 193
            :.::..|.::..|...|.|||||..:  ....:|.||.....|...:
Human   149 QVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTD------------------ 195

  Fly   194 WNSDAIDVA-ALYNDVKNKKTS--------------SSVGQL----------------------- 220
            :.||..|.. .|:|..:....:              ||.|.|
Human   196 FTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFP 260

  Fly   221 PKLWKNMHPCMVLMQMRPQTTFKFLGSSGENR-KVFSMGVSVDNCEFKADGPTKKDARRKVAALV 284
            |...||  |.|:|.::||...:.||..|||:. |.|.|.|.||...|:..|..||.|:.:.|...
Human   261 PPSGKN--PVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSA 323

  Fly   285 CNKLFGTDYPQ 295
            ...:|.....|
Human   324 LAAIFNLHLDQ 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12493	NP_647927.3	DSRM_SF	95..155	CDD:444671	20/61 (33%)
		DSRM_SF	227..284	CDD:444671	22/57 (39%)
ADARB1	XP_047296616.1	DSRM_RED1_rpt1	106..177	CDD:380724	21/70 (30%)
		DSRM_RED1_rpt2	263..332	CDD:380727	25/70 (36%)
		ADEAMc	353..769	CDD:214718