Protein Alignment CG18418 and SLC25A11

DIOPT Version :9

• Sequence 1: NP_647924.2
• Gene: CG18418 / 38572
• FlyBaseID: FBgn0035568
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: XP_024306762.1
• Gene: SLC25A11 / 8402
• HGNCID: 10981
• Length: 342
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 165/331 - (49%)
• Similarity: 215/331 - (64%)
• Gaps: 33/331 - (9%)

  Fly     6 GVEKK--TVPTHMKFVMGGTSGMLATCIVQPLDLLKTRMQISGT-LGTREYKNSFEVLSKVLKNE 67
            |::.|  |.|..:||:.||.:||.||..||||||:|.|||:||. ..|||||.||..|:.:||.|
Human    11 GIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAE 75

  Fly    68 GILSLYNG----------------------------LSAGLLRQATYTSAKMGVYQMELDWYRKN 104
            |:..:|.|                            ||||||||||||:.::|:|.:..:.....
Human    76 GLRGIYTGYWGLRMEGRLWVGSSRPWPDMLTPLLLRLSAGLLRQATYTTTRLGIYTVLFERLTGA 140

  Fly   105 FGNYPSMVASMTMGIVAGAFGAMCGNPAEVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGV 169
            .|..|..:....:|:.|||.||..|.|||||||||.:|.||..:.||.||||.:|.:||.::|||
Human   141 DGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGV 205

  Fly   170 VALWRGCLPTVGRAMVVNMVQLASYSLMKNQL--HGYLSEGIPLHLTAALVSGLLTSVTSMPLDM 232
            :.|||||:||:.||:|||..||||||..|..|  .||.|:.|..|..|:::|||:|:..|||:|:
Human   206 LTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDI 270

  Fly   233 AKTRIQQMKVIDGKPEYSGTIDVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNKAY 297
            ||||||.|::|||||||...:|||.||::.||.|::|||||||..|:||||:.:|:|||||||||
Human   271 AKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAY 335

  Fly   298 SKHMLS 303
            .:..||
Human   336 KRLFLS 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:278578	52/128 (41%)
		PTZ00169	18..296	CDD:240302	155/308 (50%)
		Mito_carr	109..205	CDD:278578	53/97 (55%)
		Mito_carr	208..300	CDD:278578	55/91 (60%)
SLC25A11	XP_024306762.1	Mito_carr	24..>85	CDD:278578	34/60 (57%)
		Mito_carr	144..241	CDD:278578	52/96 (54%)
		Mito_carr	243..337	CDD:278578	56/93 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S777
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0004406
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101430
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.670