DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18418 and DIC2

DIOPT Version :9

Sequence 1:	NP_647924.2	Gene:	CG18418 / 38572	FlyBaseID:	FBgn0035568	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_194188.1	Gene:	DIC2 / 828559	AraportID:	AT4G24570	Length:	313	Species:	Arabidopsis thaliana

Alignment Length:	308	Identity:	120/308 - (38%)
Similarity:	172/308 - (55%)	Gaps:	35/308 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FVMGGTSGMLATCIVQPLDLLKTRMQISGTLGTR----------EYKNS-----FEVLSKV---- 63
            ||.||.:.::|.|...||||:|.|:|:.|...:.          .:.||     .|..|.|
plant     6 FVEGGIASVIAGCSTHPLDLIKVRLQLHGEAPSTTTVTLLRPALAFPNSSPAAFLETTSSVPKVG 70

  Fly    64 --------LKNEGILSLYNGLSAGLLRQATYTSAKMGVYQ-MELDWYRKNFGNYPSMVASMTMGI 119
                    :|:||..:|::|:||.||||..|::.:||:|: ::..|.....|.. ::...:..|:
plant    71 PISLGINIVKSEGAAALFSGVSATLLRQTLYSTTRMGLYEVLKNKWTDPESGKL-NLSRKIGAGL 134

  Fly   120 VAGAFGAMCGNPAEVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRGCLPTVGRAM 184
            |||..||..||||:||::||.:|.||....||||..||||...:||.|||.:||||...|:.|||
plant   135 VAGGIGAAVGNPADVAMVRMQADGRLPLAQRRNYAGVGDAIRSMVKGEGVTSLWRGSALTINRAM 199

  Fly   185 VVNMVQLASYSLMKNQL--HGYLSEGIPLHLTAALVSGLLTSVTSMPLDMAKTRIQQMKVIDGKP 247
            :|...|||||...|..:  :|.:::|:..|:.|:..:|.:.||.|.|:|:.|||:..|||    .
plant   200 IVTAAQLASYDQFKEGILENGVMNDGLGTHVVASFAAGFVASVASNPVDVIKTRVMNMKV----G 260

  Fly   248 EYSGTIDVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNK 295
            .|.|..|...|.:|.|||.|::|||.|.:.|.||.|:..||.|||:.|
plant   261 AYDGAWDCAVKTVKAEGAMALYKGFVPTVCRQGPFTVVLFVTLEQVRK 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:278578	36/117 (31%)
		PTZ00169	18..296	CDD:240302	120/308 (39%)
		Mito_carr	109..205	CDD:278578	46/97 (47%)
		Mito_carr	208..300	CDD:278578	38/88 (43%)
DIC2	NP_194188.1	Mito_carr	3..118	CDD:395101	35/111 (32%)
		Mito_carr	122..220	CDD:395101	46/98 (47%)
		Mito_carr	225..312	CDD:395101	38/88 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H117313
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D892773at2759
OrthoFinder	1	1.000	-	-		FOG0004406
OrthoInspector	1	1.000	-	-		otm2939
orthoMCL	1	0.900	-	-		OOG6_101430
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.830