DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18418 and UCP5

DIOPT Version :9

Sequence 1:	NP_647924.2	Gene:	CG18418 / 38572	FlyBaseID:	FBgn0035568	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_179836.1	Gene:	UCP5 / 816783	AraportID:	AT2G22500	Length:	313	Species:	Arabidopsis thaliana

Alignment Length:	307	Identity:	116/307 - (37%)
Similarity:	178/307 - (57%)	Gaps:	25/307 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FVMGGTSGMLATCIVQPLDLLKTRMQISG-------------TLGTREYKNS-------FEVLSK 62
            |..||.:.::|.|...||||:|.|||:.|             ...|....|:       ..|.|:
plant     6 FAEGGIASIVAGCSTHPLDLIKVRMQLQGESAPIQTNLRPALAFQTSTTVNAPPLRVGVIGVGSR 70

  Fly    63 VLKNEGILSLYNGLSAGLLRQATYTSAKMGVYQ-MELDWYRKNFGNYPSMVASMTMGIVAGAFGA 126
            :::.||:.:|::|:||.:|||..|::.:||:|. ::.:|........| ::..:..|.:|||.||
plant    71 LIREEGMRALFSGVSATVLRQTLYSTTRMGLYDIIKGEWTDPETKTMP-LMKKIGAGAIAGAIGA 134

  Fly   127 MCGNPAEVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRGCLPTVGRAMVVNMVQL 191
            ..||||:||::||.:|.||...||||||:|.||..::::.|||.:||||...|:.|||:|...||
plant   135 AVGNPADVAMVRMQADGRLPLTDRRNYKSVLDAITQMIRGEGVTSLWRGSSLTINRAMLVTSSQL 199

  Fly   192 ASYSLMKNQL--HGYLSEGIPLHLTAALVSGLLTSVTSMPLDMAKTRIQQMKVIDG-KPEYSGTI 253
            |||..:|..:  .|.|.:|:..|::|:..:|.:.||.|.|:|:.|||:..|||:.| .|.|.|.:
plant   200 ASYDSVKETILEKGLLKDGLGTHVSASFAAGFVASVASNPVDVIKTRVMNMKVVAGVAPPYKGAV 264

  Fly   254 DVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNKAYSKH 300
            |...|.:|.||..:::|||.|.:.|..|.|:..||.|||:.|.:..:
plant   265 DCALKTVKAEGIMSLYKGFIPTVSRQAPFTVVLFVTLEQVKKLFKDY 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:278578	32/110 (29%)
		PTZ00169	18..296	CDD:240302	115/301 (38%)
		Mito_carr	109..205	CDD:278578	46/97 (47%)
		Mito_carr	208..300	CDD:278578	37/92 (40%)
UCP5	NP_179836.1	Mito_carr	3..106	CDD:395101	31/99 (31%)
		Mito_carr	<136..213	CDD:395101	38/76 (50%)
		Mito_carr	216..311	CDD:395101	37/94 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H117313
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D892773at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2939
orthoMCL	1	0.900	-	-		OOG6_101430
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2168
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.830