Protein Alignment CG18418 and UCP1

DIOPT Version :10

• Sequence 1: NP_647924.2
• Gene: CG18418 / 38572
• FlyBaseID: FBgn0035568
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_068605.1
• Gene: UCP1 / 7350
• HGNCID: 12517
• Length: 307
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 90/284 - (31%)
• Similarity: 142/284 - (50%)
• Gaps: 12/284 - (4%)

  Fly    22 GTSGMLATCIVQPLDLLKTRMQISG---TLGTREYKNSFEVLSKVLKNEGILSLYNGLSAGLLRQ 83
            |.:..||..|..|||..|.|:|:.|   |.....||.....::.|:|.||.:.||:||.|||.||
Human    21 GIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQ 85

  Fly    84 ATYTSAKMGVYQMELDWYRKNFGNYPSMVASMTMGIVAGAFGAMCGNPAEVALIRMMSDNRLMPE 148
            .:..|.::|:|....::........||:.:.:..|:..|......|.|.||..:|:.:.:.|...
Human    86 ISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGI 150

  Fly   149 DRRNYKNVGDAFVRIVKDEGVVALWRGCLPTVGRAMVVNMVQLASYSLMKNQL--HGYLSEGIPL 211
            ..| |....:|:..|...||:..||:|..|.:.|::::|..:|.:|.|||...  :..|::.:|.
Human   151 KPR-YTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPC 214

  Fly   212 HLTAALVSGLLTSVTSMPLDMAKTRIQQMKVIDGKP-EYSGTIDVLKKVLKNEGAFAVWKGFTPY 275
            ||.:||::|...:..|.|:|:.|||.     |:..| :|....:...||..|||..|.:||..|.
Human   215 HLVSALIAGFCATAMSSPVDVVKTRF-----INSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPS 274

  Fly   276 LMRMGPHTIFSFVFLEQMNKAYSK 299
            .:|:|...:..||..||:.:..||
Human   275 FLRLGSWNVIMFVCFEQLKRELSK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:395101	30/88 (34%)
		Mito_carr	109..205	CDD:395101	27/97 (28%)
		Mito_carr	208..300	CDD:395101	32/93 (34%)
UCP1	NP_068605.1	Mito_carr	10..104	CDD:395101	30/82 (37%)
		Solcar 1	11..102		30/80 (38%)
		Mito_carr	111..206	CDD:395101	27/95 (28%)
		Solcar 2	111..201		27/90 (30%)
		Solcar 3	210..295		30/89 (34%)
		Mito_carr	215..300	CDD:395101	31/89 (35%)