DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18418 and slc25a11

DIOPT Version :9

Sequence 1:	NP_647924.2	Gene:	CG18418 / 38572	FlyBaseID:	FBgn0035568	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001002099.1	Gene:	slc25a11 / 415189	ZFINID:	ZDB-GENE-040625-79	Length:	308	Species:	Danio rerio

Alignment Length:	297	Identity:	162/297 - (54%)
Similarity:	211/297 - (71%)	Gaps:	5/297 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KTVPTHMKFVMGGTSGMLATCIVQPLDLLKTRMQISGTLGT--REYKNSFEVLSKVLKNEGILSL 72
            ||.|..:||:.||.:||.||..||||||:|.|||:||. |:  ||||.||..:..:|:|||:..:
Zfish    11 KTSPKSIKFLFGGLAGMGATVFVQPLDLVKNRMQLSGQ-GSKAREYKTSFHAVGSILRNEGVRGI 74

  Fly    73 YNGLSAGLLRQATYTSAKMGVYQMELDWYRKNFGNYPSMVASMTMGIVAGAFGAMCGNPAEVALI 137
            |.|||||||||||||:.::|:|.:..:...|..|..|:......:|:.|||.||..|.|||||||
Zfish    75 YTGLSAGLLRQATYTTTRLGIYTILFERMSKADGTPPNFFMKALIGMTAGATGAFVGTPAEVALI 139

  Fly   138 RMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRGCLPTVGRAMVVNMVQLASYSLMKNQL- 201
            ||.:|.||.|:.||.|.||.:|.|||.::|||..|||||:||:.||:|||..||||||..|..|
Zfish   140 RMTADGRLPPDQRRGYTNVFNALVRITREEGVTTLWRGCIPTMARAVVVNAAQLASYSQSKQALL 204

  Fly   202 -HGYLSEGIPLHLTAALVSGLLTSVTSMPLDMAKTRIQQMKVIDGKPEYSGTIDVLKKVLKNEGA 265
             .||..:.|..|..|:::|||:|:..|||:|:.|||||.|::|||||||:..:|||.||::|||.
Zfish   205 DSGYFRDDILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYNNGLDVLVKVIRNEGF 269

  Fly   266 FAVWKGFTPYLMRMGPHTIFSFVFLEQMNKAYSKHML 302
            |::|||||||..|:||||:.:|:|||||||.|..:.|
Zfish   270 FSLWKGFTPYYARLGPHTVLTFIFLEQMNKFYKIYFL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:278578	52/99 (53%)
		PTZ00169	18..296	CDD:240302	155/281 (55%)
		Mito_carr	109..205	CDD:278578	54/97 (56%)
		Mito_carr	208..300	CDD:278578	54/91 (59%)
slc25a11	NP_001002099.1	Mito_carr	18..96	CDD:278578	46/78 (59%)
		PTZ00169	19..300	CDD:240302	155/281 (55%)
		Mito_carr	110..207	CDD:278578	53/96 (55%)
		Mito_carr	213..305	CDD:278578	54/91 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590898
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0004406
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101430
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.720