DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18418 and Tyler

DIOPT Version :9

Sequence 1:	NP_647924.2	Gene:	CG18418 / 38572	FlyBaseID:	FBgn0035568	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_608327.2	Gene:	Tyler / 3772349	FlyBaseID:	FBgn0031038	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	65/318 - (20%)
Similarity:	115/318 - (36%)	Gaps:	114/318 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GMLATCIVQPLDLLKTRMQISGTLGTREYKNSFEVLSKVLKNEGILSLYNGLSAGLLRQATYTSA 89
            |::.|.:|.||:::|||:|....:..|      ..:||:     ....:|||...:.|.:.....
  Fly    56 GLITTFVVTPLEVVKTRVQTQHAIRQR------PTVSKL-----CYVYHNGLMTHVCRSSDICVP 109

  Fly    90 KMGVYQMELDWYRKNFGNYPSMVASMTMGIVAGAFGAMCGNPAEVALIRMMSDNRLMPEDRRNYK 154
            |.|                                                .|    |::.|..:
  Fly   110 KPG------------------------------------------------RD----PQNLRPLR 122

  Fly   155 NVGDAFVRIVKDEGVVALWRGCLPTVGRAMVVNMVQLASYSLMKNQL-HGYL------------- 205
            ...||||:||...|...||.|..||:..|:...::...:|..:||.| |.||
  Fly   123 GAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQ 187

  Fly   206 -------------SEGIPLHLTA-----------ALVSGL------LTSVTSMPLDMAKTRIQQM 240
                         :.||.:..||           .:.||:      :|::|  |::|.:.::|..
  Fly   188 VPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAIT--PIEMVRIKMQSE 250

  Fly   241 KVIDGKPEYSGTIDVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNKAYS 298
            .:     .|:....||:.:::..|...:|:|:.|.:||..|.:...:...|.:.:|:|
  Fly   251 YM-----TYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIKRAFS 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:278578	18/82 (22%)
		PTZ00169	18..296	CDD:240302	63/314 (20%)
		Mito_carr	109..205	CDD:278578	21/96 (22%)
		Mito_carr	208..300	CDD:278578	24/108 (22%)
Tyler	NP_608327.2	Mito_carr	41..171	CDD:278578	38/177 (21%)
		Mito_carr	216..302	CDD:278578	18/92 (20%)
		Mito_carr	306..429	CDD:278578
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441486
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930