DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18418 and Ant2

DIOPT Version :9

Sequence 1:	NP_647924.2	Gene:	CG18418 / 38572	FlyBaseID:	FBgn0035568	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001259432.1	Gene:	Ant2 / 32008	FlyBaseID:	FBgn0025111	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	61/208 - (29%)
Similarity:	90/208 - (43%)	Gaps:	30/208 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GVEKKTVPTHMKF--------VMGGTSGMLATCIVQPLDLLKTRMQIS-GTLGTREYKNSFEVLS 61
            ||:|     |.:|        ..||.:|..:.|.|.|||..:||:... |..|.||:....:.|.
  Fly   112 GVDK-----HKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGGNREFNGLIDCLM 171

  Fly    62 KVLKNEGILSLYNGLSAGLLRQATYTSAKMGVYQMELDWY--RKNFGNYPSMVASMTMGIVAGAF 124
            ||:|::|.:.||.|....:.....|.:|..|.|....|:.  .|:...|.|...:..:..|||
  Fly   172 KVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLPNPKSTPFYVSWAIAQVVTTVAG-- 234

  Fly   125 GAMCGNPAEVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRGCLPTV----GRAMV 185
              :...|.:....|||..:.| .:....|||....::.|.|.||:.|.::|.|..:    |.|:|
  Fly   235 --IASYPFDTVRRRMMMQSGL-KKSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGGALV 296

  Fly   186 VNMVQLASYSLMK 198
                 ||.|..||
  Fly   297 -----LALYDEMK 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18418	NP_647924.2	Mito_carr	10..108	CDD:278578	30/108 (28%)
		PTZ00169	18..296	CDD:240302	57/196 (29%)
		Mito_carr	109..205	CDD:278578	27/94 (29%)
		Mito_carr	208..300	CDD:278578
Ant2	NP_001259432.1	PTZ00169	15..305	CDD:240302	61/208 (29%)
		Mito_carr	17..111	CDD:278578
		Mito_carr	119..215	CDD:278578	28/95 (29%)
		Mito_carr	218..307	CDD:278578	28/97 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840