DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7514 and SLC25A27

DIOPT Version :9

Sequence 1:NP_647923.1 Gene:CG7514 / 38571 FlyBaseID:FBgn0035567 Length:301 Species:Drosophila melanogaster
Sequence 2:NP_004268.3 Gene:SLC25A27 / 9481 HGNCID:21065 Length:323 Species:Homo sapiens


Alignment Length:302 Identity:82/302 - (27%)
Similarity:141/302 - (46%) Gaps:33/302 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 PGYMMYINGGLAGMLGTCIVQPLDLVKTRMQIS-----ATTGE-------YKSSFDCLLKVFKNE 63
            |....::..|.|..:......||||.|||:|:.     |..|:       |:......|.:.:.|
Human    18 PRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEE 82

  Fly    64 GILALYNGLSAGLMRQATYTTARMGFYQ--MEIDAYRKQFNAPPTVLASMGMGILAGAFGAMFGN 126
            |.|.|:.|::..:.|...|:..||..|:  .|:...:.:....|...:.:| |::||..|....|
Human    83 GFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIG-GMMAGVIGQFLAN 146

  Fly   127 PAEVALIRM-MSDNRLPPAERRNYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQLASY 190
            |.::..::| |...|....:...:.||.:||.:|:.:.|:..||.|.:|.:.||.:|||..|.:|
Human   147 PTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTY 211

  Fly   191 SQLKAAFSEYF-------SGLSLHIAAAMMSGLLTTIASMPLDMAKTRIQQQKTAE------YKG 242
            ..:|    .|.       ..:..|..:::.|||:.:|...|.|:.|:||..|...:      ||.
Human   212 DTVK----HYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKS 272

  Fly   243 TMDVLMKVSKNEGIASLWKGFTPYLCRLGPHTVFAFIFLEQL 284
            :.|.|::..:.||..||:|||.|...|:.|.::..::..|::
Human   273 STDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKI 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7514NP_647923.1 PTZ00169 16..287 CDD:240302 81/297 (27%)
Mito_carr 19..90 CDD:278578 23/82 (28%)
Mito_carr 104..201 CDD:278578 29/97 (30%)
Mito_carr 207..284 CDD:278578 26/82 (32%)
SLC25A27NP_004268.3 Mito_carr 20..118 CDD:365909 25/97 (26%)
Solcar 1 21..115 24/93 (26%)
Mito_carr 125..219 CDD:365909 30/98 (31%)
Solcar 2 125..217 29/96 (30%)
Solcar 3 226..317 26/89 (29%)
Mito_carr 227..317 CDD:365909 26/88 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0759
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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