DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7514 and UCP1

DIOPT Version :9

Sequence 1:NP_647923.1 Gene:CG7514 / 38571 FlyBaseID:FBgn0035567 Length:301 Species:Drosophila melanogaster
Sequence 2:NP_068605.1 Gene:UCP1 / 7350 HGNCID:12517 Length:307 Species:Homo sapiens


Alignment Length:281 Identity:93/281 - (33%)
Similarity:138/281 - (49%) Gaps:17/281 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 NGGLAGMLGTCIVQPLDLVKTRMQI-----SATTGEYKSSFDCLLKVFKNEGILALYNGLSAGLM 77
            :.|:|..|...|..|||..|.|:|:     :::...||.....:..|.|.||.:.||:||.|||.
Human    19 SAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQ 83

  Fly    78 RQATYTTARMGFYQMEIDAYRKQFNAPPTVLASMGMGILA----GAFGAMFGNPAEVALIRMMSD 138
            ||.:..:.|:|.|    |..::...|......|:|..|||    |......|.|.||..:|:.:.
Human    84 RQISSASLRIGLY----DTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQ 144

  Fly   139 NRLPPAERRNYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQLASYSQLKAAFSE---Y 200
            :.|...:.| |||..||:..|...||:..||||..|.:.|::|:|..:|.:|..:|.||.:   .
Human   145 SHLHGIKPR-YTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNIL 208

  Fly   201 FSGLSLHIAAAMMSGLLTTIASMPLDMAKTRIQQQKTAEYKGTMDVLMKVSKNEGIASLWKGFTP 265
            ...:..|:.:|:::|...|..|.|:|:.|||.......:||...:..|||..|||..:.:||..|
Human   209 ADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVP 273

  Fly   266 YLCRLGPHTVFAFIFLEQLTK 286
            ...|||...|..|:..|||.:
Human   274 SFLRLGSWNVIMFVCFEQLKR 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7514NP_647923.1 PTZ00169 16..287 CDD:240302 93/281 (33%)
Mito_carr 19..90 CDD:278578 27/75 (36%)
Mito_carr 104..201 CDD:278578 34/103 (33%)
Mito_carr 207..284 CDD:278578 27/76 (36%)
UCP1NP_068605.1 Mito_carr 10..104 CDD:278578 29/88 (33%)
Solcar 1 11..102 29/86 (34%)
Mito_carr 111..206 CDD:278578 34/95 (36%)
Solcar 2 111..201 32/90 (36%)
Solcar 3 210..295 29/85 (34%)
Mito_carr 215..300 CDD:278578 29/80 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0759
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54059
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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