DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7514 and Slc25a35

DIOPT Version :9

Sequence 1:	NP_647923.1	Gene:	CG7514 / 38571	FlyBaseID:	FBgn0035567	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001102503.1	Gene:	Slc25a35 / 497933	RGDID:	1598229	Length:	300	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	88/299 - (29%)
Similarity:	144/299 - (48%)	Gaps:	28/299 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MMYINGGLAGMLGTCI-VQPLDLVKTRMQISATTGE----------YKSSFDCLLKVFKNEGILA 67
            |.::..|:|. .|.|: ..||::||||||:.   ||          |::.|.....:.|.:|:.|
  Rat     1 MDFLMSGVAA-CGACVFTNPLEVVKTRMQLQ---GELQAPGTYQRHYRNVFHAFFTIGKVDGLAA 61

  Fly    68 LYNGLSAGLMRQATYTTARMGFYQM-EIDAYRKQFNAPPTVLASMGMGILAGAFGAMFGNPAEVA 131
            |..||...|:.|......|:|.|.: |...|.:......:.:.|...|.|||..||..|:|..:.
  Rat    62 LQKGLGPALLYQFLMNGIRLGTYGLAESGGYLRTKEGTHSPVRSAAAGALAGVMGAYLGSPIYMV 126

  Fly   132 LIRMMSD--NRLPPAERRNYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQLASYSQLK 194
            ...:.:.  :.:....:..:.|:..|...|.:..|::.||:|.:..:.|.:|.:..||.::|..|
  Rat   127 KTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSTK 191

  Fly   195 AAFS--EYFSGLS--LHIAAAMMSGLLTTIASMPLDMAKTRIQQQKT------AEYKGTMDVLMK 249
            ...|  |.|...|  :.:||||:||:...:|..|.|:|.||:..|.|      ..|:|.:|.|::
  Rat   192 DLLSQWEIFPPQSWKVALAAAMVSGVAVVLAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQ 256

  Fly   250 VSKNEGIASLWKGFTPYLCRLGPHTVFAFIFLEQLTKAY 288
            .::.||:..::||......||||||:.:..|.:||...|
  Rat   257 TARTEGLFGMYKGIGASYFRLGPHTILSLFFWDQLRSFY 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7514	NP_647923.1	PTZ00169	16..287	CDD:240302	86/294 (29%)
		Mito_carr	19..90	CDD:278578	26/81 (32%)
		Mito_carr	104..201	CDD:278578	24/100 (24%)
		Mito_carr	207..284	CDD:278578	29/82 (35%)
Slc25a35	NP_001102503.1	Mito_carr	2..84	CDD:395101	26/85 (31%)
		Mito_carr	98..195	CDD:395101	22/96 (23%)
		Mito_carr	209..298	CDD:395101	32/87 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910