Protein Alignment CG7514 and SLC25A35

DIOPT Version :10

• Sequence 1: NP_647923.1
• Gene: CG7514 / 38571
• FlyBaseID: FBgn0035567
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_001307799.1
• Gene: SLC25A35 / 399512
• HGNCID: 31921
• Length: 300
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 89/299 - (29%)
• Similarity: 143/299 - (47%)
• Gaps: 28/299 - (9%)

  Fly    14 MMYINGGLAGMLGTCI-VQPLDLVKTRMQISATTGE----------YKSSFDCLLKVFKNEGILA 67
            |.::..|||. .|.|: ..||::||||||:.   ||          |::.|...:.:.|.:|:.|
Human     1 MDFLMSGLAA-CGACVFTNPLEVVKTRMQLQ---GELQAPGTYQRHYRNVFHAFITIGKVDGLAA 61

  Fly    68 LYNGLSAGLMRQATYTTARMGFYQM-EIDAYRKQFNAPPTVLASMGMGILAGAFGAMFGNPAEVA 131
            |..||:..|:.|......|:|.|.: |...|........:...|...|.:||..||..|:|..:.
Human    62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMV 126

  Fly   132 LIRMMSD--NRLPPAERRNYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQLASYSQLK 194
            ...:.:.  :.:....:..:.|:..|...|.:..|::.||:|.:..:.|.::.:..||.::|..|
Human   127 KTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191

  Fly   195 AAFS--EYFSGLS--LHIAAAMMSGLLTTIASMPLDMAKTRIQQQKT------AEYKGTMDVLMK 249
            ...|  |.|...|  |.:.||||||:...:|..|.|:|.||:..|.|      ..|:|.:|.|::
Human   192 DLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKGLMYRGILDALLQ 256

  Fly   250 VSKNEGIASLWKGFTPYLCRLGPHTVFAFIFLEQLTKAY 288
            .::.|||..::||......||||||:.:..|.:||...|
Human   257 TARTEGIFGMYKGIGASYFRLGPHTILSLFFWDQLRSLY 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7514	NP_647923.1	Mito_carr	19..90	CDD:395101	27/81 (33%)
		Mito_carr	104..201	CDD:395101	22/100 (22%)
		Mito_carr	207..284	CDD:395101	30/82 (37%)
SLC25A35	NP_001307799.1	Solcar 1	1..90		30/92 (33%)
		Mito_carr	2..84	CDD:395101	27/85 (32%)
		Solcar 2	100..193		20/92 (22%)
		PTZ00169	<122..294	CDD:240302	50/171 (29%)
		Solcar 3	203..294		34/90 (38%)
		Mito_carr	209..298	CDD:395101	33/87 (38%)