DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7514 and Tyler

DIOPT Version :9

Sequence 1:	NP_647923.1	Gene:	CG7514 / 38571	FlyBaseID:	FBgn0035567	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_608327.2	Gene:	Tyler / 3772349	FlyBaseID:	FBgn0031038	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	311	Identity:	59/311 - (18%)
Similarity:	104/311 - (33%)	Gaps:	105/311 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LAGMLGTCIVQPLDLVKTRMQISATTGEYKSSFDCLLKVFKNEGILALYNGLSAGLMRQATYTTA 85
            :.|::.|.:|.||::||||:|......: :.:...|..|:        :|||...:.|.:.....
  Fly    54 VGGLITTFVVTPLEVVKTRVQTQHAIRQ-RPTVSKLCYVY--------HNGLMTHVCRSSDICVP 109

  Fly    86 RMGFYQMEIDAYRKQFNAPPTVLASMGMGILAGAFGAMFGNPAEVALIRMMSDNRLPPAERRNYT 150
            :.|                                                    ..|...|...
  Fly   110 KPG----------------------------------------------------RDPQNLRPLR 122

  Fly   151 GVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQLASYSQLKAAFSEYF--------SGL--- 204
            |.::|||:||...|...||.|..||:..|:...::...:|..:|.:.|..:        ||:
  Fly   123 GAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQ 187

  Fly   205 ----------------------------SLHIAAAMMSGL----LTTIASMPLDMAKTRIQQQKT 237
                                        ||.....|.||:    :...|..|::|.:.::|.:..
  Fly   188 VPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIKMQSEYM 252

  Fly   238 AEYKGTMDVLMKVSKNEGIASLWKGFTPYLCRLGPHTVFAFIFLEQLTKAY 288
            . |.....||..:.:..||..||:|:.|.:.|..|.:...:...|.:.:|:
  Fly   253 T-YAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIKRAF 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7514	NP_647923.1	PTZ00169	16..287	CDD:240302	58/308 (19%)
		Mito_carr	19..90	CDD:278578	17/68 (25%)
		Mito_carr	104..201	CDD:278578	18/96 (19%)
		Mito_carr	207..284	CDD:278578	19/80 (24%)
Tyler	NP_608327.2	Mito_carr	41..171	CDD:278578	34/177 (19%)
		Mito_carr	216..302	CDD:278578	21/86 (24%)
		Mito_carr	306..429	CDD:278578
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930