DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7514 and SLC25A10

DIOPT Version :9

Sequence 1:	NP_647923.1	Gene:	CG7514 / 38571	FlyBaseID:	FBgn0035567	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001257882.1	Gene:	SLC25A10 / 1468	HGNCID:	10980	Length:	406	Species:	Homo sapiens

Alignment Length:	170	Identity:	61/170 - (35%)
Similarity:	88/170 - (51%)	Gaps:	4/170 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GGLAGMLGTCIVQPLDLVKTRMQISATTGEYKSSFDCL-LKVFKNEGILALYNGLSAGLMRQATY 82
            ||||.....|...||||:|..:|   |..|.|.....: |:|.:.:||||||:||||.|.||.||
Human    13 GGLASCGAACCTHPLDLLKVHLQ---TQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTY 74

  Fly    83 TTARMGFYQMEIDAYRKQFNAPPTVLASMGMGILAGAFGAMFGNPAEVALIRMMSDNRLPPAERR 147
            :..|...|:...|...|....|......:.:|.::|..|...|.||::..:||.:|.:||..:||
Human    75 SLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRR 139

  Fly   148 NYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQL 187
            ||...|:...|:.::||:..|:.|......|..:|.:.||
Human   140 NYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7514	NP_647923.1	PTZ00169	16..287	CDD:240302	61/170 (36%)
		Mito_carr	19..90	CDD:278578	32/71 (45%)
		Mito_carr	104..201	CDD:278578	26/84 (31%)
		Mito_carr	207..284	CDD:278578
SLC25A10	NP_001257882.1	Mito_carr	13..93	CDD:278578	35/82 (43%)
SLC25A10	NP_001257882.1	Mito_carr	95..179	CDD:278578	24/83 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810