Sequence 1: | NP_647918.2 | Gene: | HDAC1 / 38565 | FlyBaseID: | FBgn0015805 | Length: | 521 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_848512.1 | Gene: | HDAC9 / 9734 | HGNCID: | 14065 | Length: | 1069 | Species: | Homo sapiens |
Alignment Length: | 458 | Identity: | 122/458 - (26%) |
---|---|---|---|
Similarity: | 193/458 - (42%) | Gaps: | 121/458 - (26%) |
- Green bases have known domain annotations that are detailed below.
Fly 26 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQ 90
Fly 91 RFNVGEDCPVFDGLYEFCQLSAGG--------------------SVAAAVKLNKQASEICINWGG 135
Fly 136 GL-----------HHAKKSEASGFCYVNDIVLGILELLKYHQ------RVLYIDIDVHHGDGVEE 183
Fly 184 AFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMD----DDAYESIFVPI 242
Fly 243 ISKVMETFQPAAVVLQCGADSLTGDR--LGCFNLTVK--GH----------GKCVEFVKKYNLPF 293
Fly 294 LMVGGGGYTIRNVSRCWTYETSV-ALAVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNTSEYL 357
Fly 358 EK---IKNRLFENLRM--LPHA---PGVQIQAIPE--DAINDESDDEDKVDKDDRLPQSDKDKRI 412
Fly 413 VPE 415 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
HDAC1 | NP_647918.2 | Arginase_HDAC | 5..372 | CDD:388375 | 111/408 (27%) |
HDAC9 | NP_848512.1 | Interaction with CTBP1. /evidence=ECO:0000250 | 23..27 | ||
ClassIIa_HDAC9_Gln-rich-N | 38..127 | CDD:197399 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 113..142 | ||||
Interaction with MEF2. /evidence=ECO:0000250 | 139..157 | ||||
Interaction with MAPK10. /evidence=ECO:0000250 | 178..346 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 186..252 | ||||
Interaction with ETV6. /evidence=ECO:0000269|PubMed:12590135 | 221..264 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 265..307 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 497..539 | ||||
HDAC_classIIa | 634..1011 | CDD:212544 | 109/399 (27%) | ||
Histone deacetylase | 634..981 | 98/364 (27%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |