Protein Alignment HDAC1 and Hdac5

DIOPT Version :10

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_063126067.1
• Gene: Hdac5 / 84580
• RGDID: 619980
• Length: 1132
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 94/342 - (27%)
• Similarity: 148/342 - (43%)
• Gaps: 63/342 - (18%)

  Fly    26 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQ 90
            ||....||:...:.|...||..|.|..|..|||.||:...|| ||...|....|.|..:.:.:..
  Rat   714 HPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHS-EYHTLLYGTSPLNRQKLDSKKL 777

  Fly    91 RFNVGEDCPVFDGLYEFCQLSAGG-SVAAAVKLNKQASEICINWGGGL----------------- 137
               :|   |:...:|  ..|..|| .|.:....|:..|...:....|.
  Rat   778 ---LG---PISQKMY--AMLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGF 834

  Fly   138 -------HHAKKSEASGFCYVNDIVLGILELLKYH---QRVLYIDIDVHHGDGVEEAFYTTDRVM 192
                   |||::|.|.|||:.|.:.: ..:||:..   .:||.:|.|:|||:|.::|||....|:
  Rat   835 AIIRPPGHHAEESTAMGFCFFNSVAI-TAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYDDPSVL 898

  Fly   193 TVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMD----DDAYESIFVPIISKVMETFQ 251
            .:|.|:|  |.:|||:|...::|.|.|..|.||:....|:|    |..|.:.|..::..:...|.
  Rat   899 YISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFS 963

  Fly   252 PAAVVLQCGADSLTG--DRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGG-------GGYTIRNVS 307
            |..|::..|.|::.|  ..||.:::|.:..|.....:      ..:.||       ||:.:..:
  Rat   964 PDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQL------MTLAGGRVVLALEGGHDLTAI- 1021

  Fly   308 RCWTYETSVA--LAVEI 322
             |...|..|:  |:||:
  Rat  1022 -CDASEACVSALLSVEL 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:450134	94/342 (27%)
Hdac5	XP_063126067.1	None