Protein Alignment HDAC1 and HDA14

DIOPT Version :10

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_567921.1
• Gene: HDA14 / 829484
• AraportID: AT4G33470
• Length: 423
• Species: Arabidopsis thaliana
• Alignment Length: 351
• Identity: 87/351 - (24%)
• Similarity: 145/351 - (41%)
• Gaps: 61/351 - (17%)

  Fly     1 MQSHSKKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRK------MEIYRPHKATA 59
            :|..:..|:.|...:.:|  :..:.||....|:....|.|....|..|      :|:.....||.
plant    57 IQQLADARLIYSVSAALG--HNKESHPECSARVPAIVNALEMNELTPKFRGSQILELANFKTATV 119

  Fly    60 DEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVF--DGLYEFCQLSAGGSVA---AA 119
            :::...|...||..|...    |.|.:.....|..|.. |.:  ...::...::||..:|   :.
plant   120 EDIANVHDKAYVFGLEKA----MDEASDSGLIFIEGSG-PTYATSTTFQDSLIAAGAGMALVDSV 179

  Fly   120 VKLNKQASEICINWG-----GGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHH 177
            :..::.:.:..|.:.     |  |||......|||...::.:......:.|  :|:..||.||||
plant   180 IAASRNSVDPPIGFALIRPPG--HHAVPKGPMGFCVFGNVAIAARHAQRTHGLKRIFIIDFDVHH 242

  Fly   178 GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPI 242
            |:|..:||.....:..:|.|:.|.| ||||.:.|||.|||:...:|:||..|..|.|..::|..|
plant   243 GNGTNDAFTEDPDIFFLSTHQDGSY-PGTGKISDIGKGKGEGTTLNLPLPGGSGDIAMRTVFEEI 306

  Fly   243 ISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGH----------------GKCVEFVKKYNL 291
            |....:.|:|..:::..|.|:...|.|.....|...:                |:||.|::
plant   307 IVPCAQRFKPDIILVSAGYDAHVLDPLANLQFTTATYYSLAKDIKRLAKEVCGGRCVFFLE---- 367

  Fly   292 PFLMVGGGGYTIRNVSRCWTYETSVA 317
                   |||.:.::|      :|||
plant   368 -------GGYNLESLS------SSVA 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:450134	86/347 (25%)
HDA14	NP_567921.1	HDAC_classII	80..387	CDD:212518	83/326 (25%)