Protein Alignment HDAC1 and Hdac8

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_006528338.1
• Gene: Hdac8 / 70315
• MGIID: 1917565
• Length: 386
• Species: Mus musculus
• Alignment Length: 346
• Identity: 148/346 - (42%)
• Similarity: 232/346 - (67%)
• Gaps: 5/346 - (1%)

  Fly    30 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNV 94
            |.|..|.|:|:..|.|:::|.|.:|..|:.:||..||:|.|::.|:.:..:...::...:: :.:
Mouse    35 PKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDEDHPDSIE-YGL 98

  Fly    95 GEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGIL 159
            |.|||..:|::::.....||::.||..|.....::.|||.||.|||||.|||||||:||.|||||
Mouse    99 GYDCPATEGIFDYAAAIGGGTITAAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGIL 163

  Fly   160 ELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVN 223
            .|.:...|:||:|:|:|||||||:||..|.:|||||.||:.. :||||||:.|:|.|||:||:||
Mouse   164 RLRRKFDRILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVN 228

  Fly   224 IPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFVKK 288
            :|::||:.|:.|..|...::.:|.:.|.|.|||||.|||::.||.:..||:|..|.|||:::|.:
Mouse   229 VPIQDGIQDEKYYHICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQ 293

  Fly   289 YNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNT 353
            :.|..|::|||||.:.|.:|||||.|.|.|...:::|:|.:::|..:|||:.|.|:||...::|.
Mouse   294 WQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNE 358

  Fly   354 SEYLEKIKNRLFENLRMLPHA 374
            ...:::|.|.:   ..::||:
Mouse   359 PHRIQQILNYI---KAVVPHS 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	146/342 (43%)
Hdac8	XP_006528338.1	HDAC8	16..370	CDD:212524	146/338 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54588
OrthoDB	1	1.010	-	-		D732770at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830