Protein Alignment HDAC1 and hdac1

DIOPT Version :10

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001025564.1
• Gene: hdac1 / 594953
• XenbaseID: XB-GENE-479583
• Length: 480
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 368/476 - (77%)
• Similarity: 420/476 - (88%)
• Gaps: 4/476 - (0%)

  Fly     5 SKKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDE 69
            :||:||||||.|:||||||||||:|||||||||||||||||||||||||||||:|:||||:|||:
 Frog     7 TKKKVCYYYDGDVGNYYYGQGHPIKPHRIRMTHNLLLNYGLYRKMEIYRPHKASAEEMTKYHSDD 71

  Fly    70 YVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWG 134
            |::|||||||||||||:||||||||||||||||||:||||||.|||||::||||||.::|.:||.
 Frog    72 YIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASSVKLNKQQTDISVNWS 136

  Fly   135 GGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKY 199
            ||||||||||||||||||||||.|||||||||||||||||:||||||||||||||||||||||||
 Frog   137 GGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY 201

  Fly   200 GEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSL 264
            ||||||||||||||||||||||||.|||||:||::||:||.|::|||||.:||:|||||||||||
 Frog   202 GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMYQPSAVVLQCGADSL 266

  Fly   265 TGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYN 329
            :||||||||||:|||.|||||:|.:|||.||:||||||||||:|||||||:|||..||.||||||
 Frog   267 SGDRLGCFNLTIKGHAKCVEFIKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYN 331

  Fly   330 DYFEYFGPDFKLHISPSNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDDE 394
            ||||||||||||||||||||||||:|||||||.||||||||||||||||:||||||:::|:|.:|
 Frog   332 DYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDSVHDDSGEE 396

  Fly   395 DKVDKDDRLPQSDKDKRIVPENEYSDSEDEGEGGRRDNRSYKG-QRKRPRLDKDTNSNKASSETS 458
            |:.|.|.|:.....||||..:.|:||||||||||||:..|:|. :|.:...:||....|   :..
 Frog   397 DEEDPDKRISIRSSDKRIACDEEFSDSEDEGEGGRRNVASFKKVKRVKTEEEKDGEEKK---DVK 458

  Fly   459 SEIKDEKEKGDGADGEESTAS 479
            .|.|.:.||.|....:|.|.|
 Frog   459 EEEKPKDEKTDSKRVKEETKS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:450134	316/366 (86%)
hdac1	NP_001025564.1	HDAC1	4..374	CDD:212534	316/366 (86%)