Protein Alignment HDAC1 and hdac3

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001016883.1
• Gene: hdac3 / 549637
• XenbaseID: XB-GENE-481106
• Length: 428
• Species: Xenopus tropicalis
• Alignment Length: 424
• Identity: 241/424 - (56%)
• Similarity: 327/424 - (77%)
• Gaps: 9/424 - (2%)

  Fly     7 KRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYV 71
            |.|.|:||.|:||::||.||||||||:.:||:|:|:||||:||.:::|::|:..:|.:|||::|:
 Frog     3 KTVAYFYDPDVGNFHYGTGHPMKPHRLSLTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67

  Fly    72 RFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGG 136
            .||:.:.|:||..:.|.:..||||:|||||.||:|||....|.|:..|.:||.:..:|.|||.||
 Frog    68 DFLQRVSPNNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGG 132

  Fly   137 LHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGE 201
            ||||||.||||||||||||:|||||||||.||||:|||:||||||:||||.|||||||||||||.
 Frog   133 LHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYVDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN 197

  Fly   202 Y-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLT 265
            | ||||||:.::||..|:||.:|:|||||:||.:|..:|.|:|.:|::.:||..:|||||||||.
 Frog   198 YFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRHLFQPVIKQVIDFYQPTCIVLQCGADSLG 262

  Fly   266 GDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYND 330
            .||||||||:::|||:||::||.:|:|.|::||||||:|||:||||||||:.:...|:.||||::
 Frog   263 CDRLGCFNLSIRGHGECVQYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDETISEELPYSE 327

  Fly   331 YFEYFGPDFKLHISPS-NMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDDE 394
            |||||.|||.||...| .:.|||:.:||::|:..:||||:||.|||.|||..:|.|.::.|..||
 Frog   328 YFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPSDILSYERTDE 392

  Fly   395 DKVDKDDRLPQSDKDKRIVPE--NEYSDSEDEGE 426
            .  |.::|   ..:|....||  ||:.|.:.:.:
 Frog   393 P--DPEER---GSEDNYSRPEASNEFYDGDHDND 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	221/366 (60%)
hdac3	NP_001016883.1	HDAC3	3..383	CDD:212529	229/379 (60%)
		Histone deacetylase	3..316		194/312 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	386..428		11/41 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D267420at33208
OrthoFinder	1	1.000	-	-		FOG0000617
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920