Protein Alignment HDAC1 and HDAC11

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Alignment Length: 303
• Identity: 84/303 - (27%)
• Similarity: 128/303 - (42%)
• Gaps: 59/303 - (19%)

  Fly    26 HPMKPHRIRMTHNLL-----LNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLR-SIRPDNMSE 84
            ||....:.:..|.||     |:.|.:     |.|.:.|.|::.:.|:.||::.|| |:....::|
  Fly    51 HPFDAAKGKHIHKLLCAQLQLDDGSF-----YEPTELTKDQLRRIHTREYLKSLRWSMNVACIAE 110

  Fly    85 Y-------NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEI--CINWGGGLHHA 140
            .       |:.:||..:.   |:        :..|.||:.|    .|.|.:.  .||.|||.||.
  Fly   111 VPLMAFVPNRYIQRSYLR---PM--------RFQAAGSILA----GKLALDYGWAINLGGGFHHC 160

  Fly   141 KKSEASGFCYVNDIVLGILELLKYH----QRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGE 201
            ......|||...||.|.|:.|.:..    :|::.:|:|.|.|:|.|..|.....|..  |..|..
  Fly   161 CSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYI--FDMYNA 223

  Fly   202 Y-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLT 265
            : :|     ||..|.:....||.  ||:..:|..|.......:.:.:..|:|..||...|.|.|.
  Fly   224 FVYP-----RDHVAKESIRCAVE--LRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLE 281

  Fly   266 GDRLGCFNLTVKGHGKCVE-------FVKKYNLPFLMVGGGGY 301
            ||.||  ||.:...| .:|       ..:...:|.:|:..|||
  Fly   282 GDPLG--NLAISAEG-VIERDRLVFSTFRALGIPVVMLLSGGY 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	84/303 (28%)
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	84/303 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48252
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840