Protein Alignment HDAC1 and hos2

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_594079.1
• Gene: hos2 / 2543643
• PomBaseID: SPAC3G9.07c
• Length: 434
• Species: Schizosaccharomyces pombe
• Alignment Length: 414
• Identity: 219/414 - (52%)
• Similarity: 299/414 - (72%)
• Gaps: 13/414 - (3%)

  Fly     6 KKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEY 70
            ||||.|:.|..:|||:||..||||||||.:|::|::.|||:.||.::.|..||..||::||.::|
pombe    25 KKRVTYHLDEQVGNYHYGDKHPMKPHRITITNHLVMGYGLHNKMSVFSPRMATFGEMSEFHREDY 89

  Fly    71 VRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGG 135
            :.||:.:.|||..::..:.|:||:|:|||||||.|||.|.|||.|:.|:.||.:..::|.|||.|
pombe    90 LDFLKRVTPDNAEQFADKFQQFNIGDDCPVFDGTYEFSQRSAGASLDASRKLVQGQTDIAINWSG 154

  Fly   136 GLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKY- 199
            ||||||:.|||||||||||||.||.:|::..||||||||:||||||::|||.:|||:|||||||
pombe   155 GLHHAKRGEASGFCYVNDIVLAILNMLRFFPRVLYIDIDIHHGDGVQQAFYESDRVLTVSFHKYN 219

  Fly   200 GEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSL 264
            |::||.||:..:.|...|||:|:|:||.||:.|:.|.|:|..||...:.||||:|:|||||||||
pombe   220 GDFFPATGNFDENGVKGGKYFALNVPLEDGIGDEQYTSLFKSIIEPTINTFQPSAIVLQCGADSL 284

  Fly   265 TGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYN 329
            ..||||.|||::..||:||.|.:.:|:|.|:|||||||:|||:|.|.||||:.:..:|.:|||..
pombe   285 GYDRLGVFNLSIHAHGECVRFTRSFNIPMLVVGGGGYTLRNVARAWCYETSICVNEQIPSELPRE 349

  Fly   330 D-YFEYFGPDFKLHISP---SNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDE 390
            . |:|:|.||:.||  |   :.:.|:||.:.||.::.|..|.||.|..||.||:|.||.| :...
pombe   350 TLYYEFFAPDYTLH--PRLTTKIENKNTPKALEDLRIRALEQLRYLGGAPSVQMQQIPPD-LTGH 411

  Fly   391 SDDEDKVDKDDRLPQSDK--DKRI 412
            .::||:...|:.|   ||  |.|:
pombe   412 LEEEDERLNDEYL---DKAVDVRV 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	202/370 (55%)
hos2	NP_594079.1	PTZ00063	25..426	CDD:240251	215/406 (53%)
		HDAC_Hos2	28..337	CDD:212540	178/308 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	65	1.000	Domainoid score	I2833
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000617
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100248
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710