Protein Alignment HDAC1 and hda-11

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_505699.3
• Gene: hda-11 / 183226
• WormBaseID: WBGene00007953
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 315
• Identity: 75/315 - (23%)
• Similarity: 123/315 - (39%)
• Gaps: 39/315 - (12%)

  Fly     6 KKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEY 70
            ::.:.|:.:.::..:.....||....:.|.....|....|.....:..|:..|.:|:|:.|..:|
 Worm    16 QRPIVYHSEYNVTAFGIEHLHPFDSSKWRRVITHLKEMNLITDETLVEPNLPTFEELTRVHDRKY 80

  Fly    71 VRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGG 135
               |:|:|....:....::........|.:...|....:|.|||:|.||....|..  ..||.||
 Worm    81 ---LKSVRNPIKAAQIVEIPFVGCLPPCIIESKLLHPLRLQAGGTVLAANLALKHG--WAINVGG 140

  Fly   136 GLHHAKKSEASGFCYVNDIVLGILELL--KYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHK 198
            |.|||..|...|||:..||.:.|.:|.  |.....:.:|:|.|.|:|....|.....|..  |..
 Worm   141 GFHHASHSGGGGFCFYADITMAIFDLFDKKAIANAIVVDLDAHQGNGHARDFADNPNVFV--FDV 203

  Fly   199 YGEY-FPGTGDLRDIGAGKGKYYAVN--IPLRDGMDDDAYESIFVPIISKVM----ETFQPA--A 254
            :..| :|...:.|..         :|  :.:.....|.:|.|.....:::.:    :|..|.  .
 Worm   204 FNPYVYPHDREARQF---------INRAVHVNGHTTDTSYLSELRKQLAQCLIDREKTTPPGFDF 259

  Fly   255 VVLQCGADSLTGDRLGCFNLTVKGHGKCV--------EFVKKYNLPFLMVGGGGY 301
            ::...|.|.|.||.||...|:    .:|:        ...|...:|..||..|||
 Worm   260 IMFNAGTDCLLGDPLGAMKLS----PQCIIARDEVVFNLAKSKGIPICMVTSGGY 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	75/315 (24%)
hda-11	NP_505699.3	HDAC_classIV	36..325	CDD:212519	74/295 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810